Literature DB >> 17949100

Cyclic sulfamidates as precursors to alkylidene pyrrolidines and piperidines.

John F Bower1, Peter Szeto, Timothy Gallagher.   

Abstract

The reaction of the dienolate of ethyl acetoacetate (and related dienolates) with a range of 1,2- and 1,3-cyclic sulfamidates provides an entry to substituted and enantiopure alkylidenated pyrrolidines and piperidines. These heterocycles function as convenient precursors to heterocyclic beta-amino acid derivatives.

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Year:  2007        PMID: 17949100     DOI: 10.1021/ol7022104

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  A stereoselective synthesis of the bromopyrrole natural product (-)-agelastatin A.

Authors:  Paul M Wehn; J Du Bois
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

2.  Nickel-Catalyzed Asymmetric Hydrogenation of Cyclic Sulfamidate Imines: Efficient Synthesis of Chiral Cyclic Sulfamidates.

Authors:  Yuanhua Liu; Zhiyuan Yi; Xuefeng Tan; Xiu-Qin Dong; Xumu Zhang
Journal:  iScience       Date:  2019-07-04
  2 in total

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