Literature DB >> 17947627

Randomized trial of a clinical decision support system: impact on the management of children with fever without apparent source.

Jolt Roukema1, Ewout W Steyerberg, Johan van der Lei, Henriëtte A Moll.   

Abstract

OBJECTIVE: To assess compliance with a clinical decision support system (CDSS) for diagnostic management of children with fever without apparent source and to study the effects of application of the CDSS on time spent in the emergency department (ED) and number of laboratory tests.
DESIGN: The CDSS was used by ED nursing staff to register children presenting with fever. The CDSS identified children that met inclusion criteria (1-36 months and fever without apparent source (FWS)) and provided patient-specific diagnostic management advice. Children at high risk for serious bacterial infection were randomized for the 'intervention' (n = 74) or the 'control' (n = 90) group. In the intervention group, the CDSS provided the advice to immediately order laboratory tests and in the control group the ED physician first assessed the children and then decided on ordering laboratory tests.
RESULTS: Compliance with registration of febrile children was 50% (683/1,399). Adherence to the advice to order laboratory tests was 82% (61/74). Children in the intervention group had a median (25(th)-75(th) percentile) length of stay at the ED of 138 (104-181) minutes. The median length of stay at the ED in the control group was 123 (83-179) minutes. Laboratory tests were significantly more frequently ordered in the intervention group (82%) than in the control group (44%, p < 0.001, chi(2) test).
CONCLUSION: Implementation of a CDSS for diagnostic management of young children with fever without apparent source was successful regarding compliance and adherence to CDSS recommendations, but had unexpected effects on patient outcome in terms of ED length of stay and number of laboratory tests. The use of the current CDSS was discontinued.

Entities:  

Mesh:

Year:  2007        PMID: 17947627      PMCID: PMC2273109          DOI: 10.1197/jamia.M2164

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  24 in total

1.  Validation and updating of predictive logistic regression models: a study on sample size and shrinkage.

Authors:  Ewout W Steyerberg; Gerard J J M Borsboom; Hans C van Houwelingen; Marinus J C Eijkemans; J Dik F Habbema
Journal:  Stat Med       Date:  2004-08-30       Impact factor: 2.373

Review 2.  Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review.

Authors:  Amit X Garg; Neill K J Adhikari; Heather McDonald; M Patricia Rosas-Arellano; P J Devereaux; Joseph Beyene; Justina Sam; R Brian Haynes
Journal:  JAMA       Date:  2005-03-09       Impact factor: 56.272

Review 3.  Field trials of medical decision-aids: potential problems and solutions.

Authors:  J Wyatt; D Spiegelhalter
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1991

4.  Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review.

Authors:  D L Hunt; R B Haynes; S E Hanna; K Smith
Journal:  JAMA       Date:  1998-10-21       Impact factor: 56.272

Review 5.  Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success.

Authors:  Kensaku Kawamoto; Caitlin A Houlihan; E Andrew Balas; David F Lobach
Journal:  BMJ       Date:  2005-03-14

Review 6.  Evaluation of the infant with fever without source: an evidence based approach.

Authors:  M Slater; S E Krug
Journal:  Emerg Med Clin North Am       Date:  1999-02       Impact factor: 2.264

7.  Electronic alerts to prevent venous thromboembolism among hospitalized patients.

Authors:  Nils Kucher; Sophia Koo; Rene Quiroz; Joshua M Cooper; Marilyn D Paterno; Boris Soukonnikov; Samuel Z Goldhaber
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

8.  Predictors of occult pneumococcal bacteremia in young febrile children.

Authors:  N Kuppermann; G R Fleisher; D M Jaffe
Journal:  Ann Emerg Med       Date:  1998-06       Impact factor: 5.721

9.  Outpatient management without antibiotics of fever in selected infants.

Authors:  M D Baker; L M Bell; J R Avner
Journal:  N Engl J Med       Date:  1993-11-11       Impact factor: 91.245

10.  Risk of bacteremia for febrile young children in the post-Haemophilus influenzae type b era.

Authors:  G M Lee; M B Harper
Journal:  Arch Pediatr Adolesc Med       Date:  1998-07
View more
  21 in total

1.  Investigating Investigation (Ab)Use: Thyroid Function Test Audit in a Tertiary Care Teaching Institute in Eastern India.

Authors:  Suchanda Sahu; Joseph John
Journal:  Indian J Clin Biochem       Date:  2021-01-15

Review 2.  The use of computerized clinical decision support systems in emergency care: a substantive review of the literature.

Authors:  Paula Bennett; Nicholas R Hardiker
Journal:  J Am Med Inform Assoc       Date:  2017-05-01       Impact factor: 4.497

3.  Derivation and validation of age and temperature specific reference values and centile charts to predict lower respiratory tract infection in children with fever: prospective observational study.

Authors:  R G Nijman; M Thompson; M van Veen; R Perera; H A Moll; R Oostenbrink
Journal:  BMJ       Date:  2012-07-03

Review 4.  Computerized clinical decision support systems for acute care management: a decision-maker-researcher partnership systematic review of effects on process of care and patient outcomes.

Authors:  Navdeep Sahota; Rob Lloyd; Anita Ramakrishna; Jean A Mackay; Jeanette C Prorok; Lorraine Weise-Kelly; Tamara Navarro; Nancy L Wilczynski; R Brian Haynes
Journal:  Implement Sci       Date:  2011-08-03       Impact factor: 7.327

Review 5.  Can computerized clinical decision support systems improve practitioners' diagnostic test ordering behavior? A decision-maker-researcher partnership systematic review.

Authors:  Pavel S Roshanov; John J You; Jasmine Dhaliwal; David Koff; Jean A Mackay; Lorraine Weise-Kelly; Tamara Navarro; Nancy L Wilczynski; R Brian Haynes
Journal:  Implement Sci       Date:  2011-08-03       Impact factor: 7.327

Review 6.  Standards for reporting randomized controlled trials in medical informatics: a systematic review of CONSORT adherence in RCTs on clinical decision support.

Authors:  K M Augestad; G Berntsen; K Lassen; J G Bellika; R Wootton; R O Lindsetmo
Journal:  J Am Med Inform Assoc       Date:  2011-07-29       Impact factor: 4.497

7.  Impact of a clinical decision model for febrile children at risk for serious bacterial infections at the emergency department: a randomized controlled trial.

Authors:  Evelien de Vos-Kerkhof; Ruud G Nijman; Yvonne Vergouwe; Suzanne Polinder; Ewout W Steyerberg; Johan van der Lei; Henriëtte A Moll; Rianne Oostenbrink
Journal:  PLoS One       Date:  2015-05-29       Impact factor: 3.240

8.  The predictive value of the NICE "red traffic lights" in acutely ill children.

Authors:  Evelien Kerkhof; Monica Lakhanpaul; Samiran Ray; Jan Y Verbakel; Ann Van den Bruel; Matthew Thompson; Marjolein Y Berger; Henriette A Moll; Rianne Oostenbrink
Journal:  PLoS One       Date:  2014-03-14       Impact factor: 3.240

9.  Clinical prediction model to aid emergency doctors managing febrile children at risk of serious bacterial infections: diagnostic study.

Authors:  Ruud G Nijman; Yvonne Vergouwe; Matthew Thompson; Mirjam van Veen; Alfred H J van Meurs; Johan van der Lei; Ewout W Steyerberg; Henriette A Moll; Rianne Oostenbrink
Journal:  BMJ       Date:  2013-04-02

10.  How well do clinical prediction rules perform in identifying serious infections in acutely ill children across an international network of ambulatory care datasets?

Authors:  Jan Y Verbakel; Ann Van den Bruel; Matthew Thompson; Richard Stevens; Bert Aertgeerts; Rianne Oostenbrink; Henriette A Moll; Marjolein Y Berger; Monica Lakhanpaul; David Mant; Frank Buntinx
Journal:  BMC Med       Date:  2013-01-15       Impact factor: 8.775

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.