Literature DB >> 17942169

The discovery of ghrelin--a personal memory.

Masayasu Kojima1.   

Abstract

The endogenous ligand for growth-hormone secretagogue receptor (GHS-R) was purified from the stomach and named it "ghrelin," after the word root "ghre" in Proto-Indo-European languages meaning "grow", since ghrelin has potent growth hormone (GH) releasing activity. Ghrelin plays important roles for maintaining growth hormone release and energy homeostasis in vertebrates. In this essay, I described my personal memory on the discovery of ghrelin in the year 1999.

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Year:  2007        PMID： 17942169     DOI： 10.1016/j.regpep.2007.09.023

Source DB:  PubMed          Journal:  Regul Pept        ISSN： 0167-0115


  9 in total

Review 1.  Hormonal regulation of gastric acid secretion.

Authors:  Mitchell L Schubert
Journal:  Curr Gastroenterol Rep       Date:  2008-12

Review 2.  Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics.

Authors:  Lee E Eiden; Ki Ann Goosens; Kenneth A Jacobson; Lorenzo Leggio; Limei Zhang
Journal:  ACS Pharmacol Transl Sci       Date:  2020-03-18

3.  Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants.

Authors:  Yu-Kyong Shin; Bronwen Martin; Wook Kim; Caitlin M White; Sunggoan Ji; Yuxiang Sun; Roy G Smith; Jean Sévigny; Matthias H Tschöp; Stuart Maudsley; Josephine M Egan
Journal:  PLoS One       Date:  2010-09-14       Impact factor: 3.240

4.  Serum level of ghrelin in umbilical cord in small and appropriate for gestational age newborn infants and its relationship to anthropometric measures.

Authors:  Abdel Hakeem A Abdel Hakeem; Samera Z Saed; Mahmoud A El Rehany; Essam E Yassin
Journal:  J Clin Neonatol       Date:  2012-07

Review 5.  Molecular mechanisms of taste recognition: considerations about the role of saliva.

Authors:  Tibor Károly Fábián; Anita Beck; Pál Fejérdy; Péter Hermann; Gábor Fábián
Journal:  Int J Mol Sci       Date:  2015-03-13       Impact factor: 5.923

Review 6.  The Impact of Ghrelin in Metabolic Diseases: An Immune Perspective.

Authors:  Jéssica Aparecida da Silva Pereira; Felipe Corrêa da Silva; Pedro Manoel Mendes de Moraes-Vieira
Journal:  J Diabetes Res       Date:  2017-09-07       Impact factor: 4.011

Review 7.  Is Ghrelin Synthesized in the Central Nervous System?

Authors:  Agustina Cabral; Eduardo J López Soto; Jacques Epelbaum; Mario Perelló
Journal:  Int J Mol Sci       Date:  2017-03-15       Impact factor: 5.923

8.  Ghrelin accelerates the growth and osteogenic differentiation of rabbit mesenchymal stem cells through the ERK1/2 pathway.

Authors:  Nan Ye; Dianming Jiang
Journal:  BMC Biotechnol       Date:  2015-06-09       Impact factor: 2.563

9.  Ghrelin attenuates the growth of HO-8910 ovarian cancer cells through the ERK pathway.

Authors:  R X Bai; W P Wang; P W Zhao; C B Li
Journal:  Braz J Med Biol Res       Date:  2016-02-02       Impact factor: 2.590
  9 in total

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