Literature DB >> 17940818

Production of cephamycin C by Streptomyces clavuligerus NT4 using solid-state fermentation.

Baburao Bussari1, Parag S Saudagar, Nikhil S Shaligram, Shrikant A Survase, Rekha S Singhal.   

Abstract

Cephamycin C is an extracellular broad spectrum beta-lactam antibiotic produced by Streptomyces clavuligerus, S. cattleya and Nocardia lactamdurans. In the present study, different substrates for solid-state fermentation were screened for maximum cephamycin C production by S. clavuligerus NT4. The fermentation parameters such as substrate concentration, moisture content, potassium dihydrogen phosphate, inoculum size and ammonium oxalate were optimized by response surface methodology (RSM). The optimized conditions yielded 21.68 +/- 0.76 mg gds(-1) of cephamycin C as compared to 10.50 +/- 1.04 mg gds(-1) before optimization. Effect of various amino acids on cephamycin C production was further studied by using RSM, which resulted in increased yield of 27.41 +/- 0.65 mg gds(-1).

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17940818     DOI： 10.1007/s10295-007-0265-x

Source DB:  PubMed          Journal:  J Ind Microbiol Biotechnol        ISSN： 1367-5435            Impact factor:   4.258


  6 in total

1.  Beta-lactam antibiotics from Streptomyces.

Authors:  R Nagarajan; L D Boeck; M Gorman; R L Hamill; C E Higgens; M M Hoehn; W M Stark; J G Whitney
Journal:  J Am Chem Soc       Date:  1971-05-05       Impact factor: 15.419

Review 2.  Control of antibiotic biosynthesis.

Authors:  J F Martin; A L Demain
Journal:  Microbiol Rev       Date:  1980-06

3.  Regulation of cephamycin C synthesis, aspartokinase, dihydrodipicolinic acid synthetase, and homoserine dehydrogenase by aspartic acid family amino acids in Streptomyces clavuligerus.

Authors:  S Mendelovitz; Y Aharonowitz
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191

4.  Application of central composite design and response surface methodology to the fermentation of olive juice by Lactobacillus plantarum and Debaryomyces hansenii.

Authors:  S Tsapatsaris; P Kotzekidou
Journal:  Int J Food Microbiol       Date:  2004-09-01       Impact factor: 5.277

5.  Utilization of rice straw for laccase production by Streptomyces psammoticus in solid-state fermentation.

Authors:  Kizhakkedathu Narayanan Niladevi; Rajeev Kumar Sukumaran; Parukuttyamma Prema
Journal:  J Ind Microbiol Biotechnol       Date:  2007-07-31       Impact factor: 3.346

6.  Cephamycins, a new family of beta-lactam antibiotics. I. Production by actinomycetes, including Streptomyces lactamdurans sp. n.

Authors:  E O Stapley; M Jackson; S Hernandez; S B Zimmerman; S A Currie; S Mochales; J M Mata; H B Woodruff; D Hendlin
Journal:  Antimicrob Agents Chemother       Date:  1972-09       Impact factor: 5.191
  6 in total
  4 in total

1.  Relevance of the light signaling machinery for cellulase expression in Trichoderma reesei (Hypocrea jecorina).

Authors:  Miklós Gyalai-Korpos; Gáspár Nagy; Zoltán Mareczky; André Schuster; Kati Réczey; Monika Schmoll
Journal:  BMC Res Notes       Date:  2010-12-07

2.  Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus.

Authors:  Carla A Leite; André P Cavallieri; Maria L G C Araujo
Journal:  BMC Microbiol       Date:  2013-12-20       Impact factor: 3.605

3.  Streptomyces spp. From Ethiopia Producing Antimicrobial Compounds: Characterization via Bioassays, Genome Analyses, and Mass Spectrometry.

Authors:  Moges Kibret; Jaime F Guerrero-Garzón; Ernst Urban; Martin Zehl; Valerie-Katharina Wronski; Christian Rückert; Tobias Busche; Jörn Kalinowski; Judith M Rollinger; Dawit Abate; Sergey B Zotchev
Journal:  Front Microbiol       Date:  2018-06-12       Impact factor: 5.640

Review 4.  Clavulanic Acid Production by Streptomyces clavuligerus: Insights from Systems Biology, Strain Engineering, and Downstream Processing.

Authors:  Víctor A López-Agudelo; David Gómez-Ríos; Howard Ramirez-Malule
Journal:  Antibiotics (Basel)       Date:  2021-01-18
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.