INTRODUCTION: The aim of our study was to investigate a potential influence of elevated serumcobalt and serumchromiumlevels on renal function at minimum 10 years after implantation of a metal-on-metal hip. MATERIALS AND METHODS: Between November 1992 and June 1994 98 patients (44 m, 54 f) with an average age of 56 (22-79) years received a metal-on-metal bearing Metasul. At the time of the 10-year follow-up, 15 patients had died and 8 were lost to follow-up. The remaining 75 patients had laboratory analysis including serumcreatinine and full blood cell count as well as chromium and cobalt serum levels. RESULTS: Ten years postoperatively the median serumcreatinine level was 0.86 (0.55-1.51) mg/dl, the serumcreatinine clearance Ccr was in the normal range. The hemogram did not differ from that measured at the time of surgery. The median serumcobalt concentration was 0.75 (0.3-50.10) microg/l and the serumchromium concentration was 0.95 (0.3-58.6) mug/l, 10 years postoperatively. CONCLUSION: Our long-term data do not show any influence of serum cobalt or chromium concentrations on renal function following total hip arthroplasty.
INTRODUCTION: The aim of our study was to investigate a potential influence of elevated serumcobalt and serumchromiumlevels on renal function at minimum 10 years after implantation of a metal-on-metal hip. MATERIALS AND METHODS: Between November 1992 and June 1994 98 patients (44 m, 54 f) with an average age of 56 (22-79) years received a metal-on-metal bearing Metasul. At the time of the 10-year follow-up, 15 patients had died and 8 were lost to follow-up. The remaining 75 patients had laboratory analysis including serumcreatinine and full blood cell count as well as chromium and cobalt serum levels. RESULTS: Ten years postoperatively the median serumcreatinine level was 0.86 (0.55-1.51) mg/dl, the serumcreatinine clearance Ccr was in the normal range. The hemogram did not differ from that measured at the time of surgery. The median serumcobalt concentration was 0.75 (0.3-50.10) microg/l and the serumchromium concentration was 0.95 (0.3-58.6) mug/l, 10 years postoperatively. CONCLUSION: Our long-term data do not show any influence of serum cobalt or chromium concentrations on renal function following total hip arthroplasty.
Authors: M Stiehler; F Zobel; F Hannemann; J Schmitt; J Lützner; S Kirschner; K-P Günther; A Hartmann Journal: Orthopade Date: 2014-01 Impact factor: 1.087
Authors: Thomas M Grupp; James J Yue; Rolando Garcia; Christian Kaddick; Bernhard Fritz; Christoph Schilling; Jens Schwiesau; Wilhelm Blömer Journal: Eur Spine J Date: 2014-06-06 Impact factor: 3.134
Authors: Henrik Dahlstrand; André Stark; Marius C Wick; Lucas Anissian; Nils P Hailer; Rüdiger J Weiss Journal: Acta Orthop Date: 2017-07-12 Impact factor: 3.717
Authors: Jennifer R Prentice; Matthew J Clark; Nigel Hoggard; Allison C Morton; Claire Tooth; Martyn N Paley; Ian Stockley; Marios Hadjivassiliou; J Mark Wilkinson Journal: PLoS One Date: 2013-06-10 Impact factor: 3.240