| Literature DB >> 17934925 |
I Skandrani1, M Ben Sghaier, A Neffati, J Boubaker, I Bouhlel, S Kilani, A Mahmoud, K Ghedira, L Chekir-Ghedira.
Abstract
This study evaluates genotoxic and antigenotoxic effects of extracts from leaves of Moricandia arvensis, which are used in traditional cooking and medicines. Extracts showed no genotoxicity when tested with the SOS Chromotest using E. coli PQ37 and PQ35 strains, except for the total oligomers flavonoids enriched extract. Petroleum ether and methanol extracts are the most active in reducing nitrofurantoin genotoxicity, whereas methanol and total oligomers flavonoids enriched extracts showed the most important inhibitory effect of H2O2 genotoxicity. In addition, these two extracts showed important free radical scavenging activity toward the DPPH. radical, whereas the chloroform extract exhibited the highest value of TEAC against ABTS+. radical.Entities:
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Year: 2007 PMID: 17934925 DOI: 10.1080/01480540701522494
Source DB: PubMed Journal: Drug Chem Toxicol ISSN: 0148-0545 Impact factor: 3.356