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Literature DB >> 17934761

Positive association between OLIG2 and schizophrenia in the Chinese Han population.

Ke Huang¹, Wei Tang, Ruqi Tang, Zhao Xu, Zhangdong He, Zhiqiang Li, Yifeng Xu, Xingwang Li, Guang He, Guoying Feng, Lin He, Yongyong Shi.

Abstract

A recent study reported that OLIG2 had a significant association with schizophrenia in the UK population. We genotyped three variants scattered among the genomic region of OLIG2, namely rs1005573, rs762178 and rs1059004 in a sample consisting of 329 schizophrenia patients and 288 controls. The results provide further evidence that the SNP rs762178 in OLIG2 seems to be a potential candidate in altering risk for schizophrenia in the Chinese Han population and worthy of further replication and functional study.

Entities: Disease Gene Mutation Species

Mesh：

Substances：

Year: 2007 PMID： 17934761 DOI： 10.1007/s00439-007-0434-z

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

4 in total

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2. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci.

Authors: Yong Yong Shi; Lin He
Journal: Cell Res Date: 2005-02 Impact factor: 25.617

3. Recognition of script-typical versus script-atypical information: effects of cognitive elaboration.

Authors: E Erdfelder; J Bredenkamp
Journal: Mem Cognit Date: 1998-09

4. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.

Authors: Lyudmila Georgieva; Valentina Moskvina; Tim Peirce; Nadine Norton; Nicholas J Bray; Lesley Jones; Peter Holmans; Stuart Macgregor; Stanley Zammit; Jennifer Wilkinson; Hywel Williams; Ivan Nikolov; Nigel Williams; Dobril Ivanov; Kenneth L Davis; Vahram Haroutunian; Joseph D Buxbaum; Nick Craddock; George Kirov; Michael J Owen; Michael C O'Donovan
Journal: Proc Natl Acad Sci U S A Date: 2006-08-04 Impact factor: 11.205

4 in total

16 in total

Review 1. Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2.

Authors: Dimphna H Meijer; Michael F Kane; Shwetal Mehta; Hongye Liu; Emily Harrington; Christopher M Taylor; Charles D Stiles; David H Rowitch
Journal: Nat Rev Neurosci Date: 2012-12 Impact factor: 34.870

2. Association of imaging classification of intracranial cerebral atherosclerotic vascular stenosis in ischemic stroke and renalase gene polymorphisms.

Authors: Xiaoying Li; Zhenzhen Wang; Yan Liu; Ruyou Zhang; Xijuan Guo; Wei Liu; Chunping Ning; Litao Sun; Jiawei Tian
Journal: J Mol Neurosci Date: 2013-09-07 Impact factor: 3.444

3. Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic Encephalopathy.

Authors: Liya Sun; Lei Xia; Mingtai Wang; Dengna Zhu; Yangong Wang; Dan Bi; Juan Song; Caiyun Ma; Chao Gao; Xiaoli Zhang; Yanyan Sun; Xiaoyang Wang; Changlian Zhu; Qinghe Xing
Journal: Neuromolecular Med Date: 2018-09-03 Impact factor: 3.843

4. Neurotoxocarosis alters myelin protein gene transcription and expression.

Authors: Lea Heuer; Martin Beyerbach; Fred Lühder; Andreas Beineke; Christina Strube
Journal: Parasitol Res Date: 2015-03-17 Impact factor: 2.289

5. Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.

Authors: Hiroshi Komatsu; Hikaru Takeuchi; Yoshie Kikuchi; Chiaki Ono; Zhiqian Yu; Kunio Iizuka; Yuji Takano; Yoshihisa Kakuto; Shunichi Funakoshi; Takashi Ono; Junko Ito; Yasuto Kunii; Mizuki Hino; Atsuko Nagaoka; Yasushi Iwasaki; Hidenaga Yamamori; Yuka Yasuda; Michiko Fujimoto; Hirotsugu Azechi; Noriko Kudo; Ryota Hashimoto; Hirooki Yabe; Mari Yoshida; Yuko Saito; Akiyoshi Kakita; Nobuo Fuse; Ryuta Kawashima; Yasuyuki Taki; Hiroaki Tomita
Journal: Schizophr Bull Date: 2020-12-01 Impact factor: 9.306

Positive association between OLIG2 and schizophrenia in the Chinese Han population.

Review 1. The power of the 3' UTR: translational control and development.

2. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci.

3. Recognition of script-typical versus script-atypical information: effects of cognitive elaboration.

4. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.

Review 1. Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2.

2. Association of imaging classification of intracranial cerebral atherosclerotic vascular stenosis in ischemic stroke and renalase gene polymorphisms.

3. Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic Encephalopathy.

4. Neurotoxocarosis alters myelin protein gene transcription and expression.

5. Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.

6. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China.

Review 7. Convergence and divergence in the etiology of myelin impairment in psychiatric disorders and drug addiction.

8. An association study on renalase polymorphisms and ischemic stroke in a Chinese population.

9. A Novel Association of the Suppressor of Cytokine Signaling 1 (SOCS1) Gene Polymorphisms in Ischemic Stroke Patients.

Review 10. Myelin, copper, and the cuprizone model of schizophrenia.