Literature DB >> 17923161

Four-dimensional multislice helical CT of the lung: qualitative comparison of retrospectively gated and static images in an ex-vivo system.

Julien Dinkel1, Thomas Welzel, Hendrik Bolte, Beata Hoffmann, Carsten Thierfelder, Ulrich Mende, Jürgen Debus, Martin Heller, Hans-Ulrich Kauczor, Juergen Biederer.   

Abstract

PURPOSE: To analyse the image quality of retrospectively gated helical CT using controlled respiratory motion of porcine lung explants.
MATERIALS AND METHODS: Five porcine lungs were examined inside a chest phantom. A silicone membrane was rhythmically inflated and deflated to simulate diaphragmatic respiration. Dynamic images (regular respiration at 8/min) and static scans (w/o respiration) at 0/25/50/75 and 100% of maximum inspiration were acquired with a 40-row detector CT scanner (rotation time 1s, pitch 0.1). Image quality on multi-planar reformations was evaluated by two observers. Partial projection artifacts, stepladder-artifacts and noise were compared for upper, middle and lower parts of the lung and different respiratory phases (scores 0-3 for absent, minimal, moderate and diagnostically relevant artifacts).
RESULTS: Partial projection effects were limited to dynamic scans (mean score 1.33). Stepladder artifacts predominated in dynamic series compared to static series (mean score 0.55 versus 0.1; p<0.001). Image noise was not related to lung motion (mean scores 0.68-0.81). All artifacts predominated close to the diaphragm compared to the upper and middle parts of the lung (p<0.001 to p=0.02, respectively). Partial projection and stepladder artifacts were less in end-inspiration and end-expiration than within the respiration (p<0.001 and p=0.17, respectively). Diagnostically relevant artifacts were noted 9 times (9/9 close to diaphragm, 7/9 partial-projection).
CONCLUSIONS: Even in ideal realistic conditions, helical 4D-CT produced tolerable artifacts which could be overcome by radiologists.

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Year:  2007        PMID: 17923161     DOI: 10.1016/j.radonc.2007.09.003

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  7 in total

1.  MRI of respiratory dynamics with 2D steady-state free-precession and 2D gradient echo sequences at 1.5 and 3 Tesla: an observer preference study.

Authors:  M Fabel; B J Wintersperger; O Dietrich; M Eichinger; C Fink; M Puderbach; H-U Kauczor; S O Schoenberg; J Biederer
Journal:  Eur Radiol       Date:  2008-09-06       Impact factor: 5.315

2.  Characterization and identification of spatial artifacts during 4D-CT imaging.

Authors:  Dongfeng Han; John Bayouth; Sudershan Bhatia; Milan Sonka; Xiaodong Wu
Journal:  Med Phys       Date:  2011-04       Impact factor: 4.071

Review 3.  [Computed tomography of the lungs. A step into the fourth dimension].

Authors:  J Dinkel; C Hintze; N Rochet; C Thieke; J Biederer
Journal:  Radiologe       Date:  2009-08       Impact factor: 0.635

4.  A comparative study of target volumes based on 18F-FDG PET-CT and ten phases of 4DCT for primary thoracic squamous esophageal cancer.

Authors:  Yanluan Guo; Jianbin Li; Peng Zhang; Yingjie Zhang
Journal:  Onco Targets Ther       Date:  2017-01-06       Impact factor: 4.147

5.  Comparison of gross tumor volume of primary oesophageal cancer based on contrast-enhanced three-dimensional, four-dimensional, and cone beam computed tomography.

Authors:  Chao-Yue Hu; Jian-Bin Li; Jin-Zhi Wang; Wei Wang; Feng-Xiang Li; Yan-Luan Guo
Journal:  Oncotarget       Date:  2017-10-05

6.  Geometrical differences in gross target volumes between 3DCT and 4DCT imaging in radiotherapy for non-small-cell lung cancer.

Authors:  Fengxing Li; Jianbin Li; Yingjie Zhang; Min Xu; Dongping Shang; Tingyong Fan; Tonghai Liu; Qian Shao
Journal:  J Radiat Res       Date:  2013-04-05       Impact factor: 2.724

7.  Changes in cardiac volume determined with repeated enhanced 4DCT during chemoradiotherapy for esophageal cancer.

Authors:  Xue Wang; Jin-Zhi Wang; Jian-Bin Li; Ying-Jie Zhang; Feng-Xiang Li; Wei Wang; Yan-Luan Guo; Qian Shao; Min Xu; Xi-Jun Liu; Yue Wang
Journal:  Radiat Oncol       Date:  2018-09-18       Impact factor: 3.481

  7 in total

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