| Literature DB >> 17916998 |
Bernd W Scheithauer1, Ana Isabel Silva, John L D Atkinson, Todd B Nippoldt, Timothy J Kaufmann, Kalman Kovacs, Eva Horvath, Ricardo Lloyd.
Abstract
Herein, we report a unique case of an adult male with a corticotrophic pituitary adenoma of silent subtype 1 exhibiting conspicuous idiopathic tumoral noncaseating granulomatous inflammation. The lesion was unassociated with clinical or laboratory evidence of either systemic sarcoidosis or infection. Histochemical and polymerase chain reaction (PCR) studies revealed neither fungi nor tubercle bacilli. We suggest that tumoral production of an as yet uncharacterized antigen may have induced the granulomatous inflammatory reaction.Entities:
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Year: 2007 PMID: 17916998 DOI: 10.1007/s12022-007-0017-5
Source DB: PubMed Journal: Endocr Pathol ISSN: 1046-3976 Impact factor: 3.943