Literature DB >> 12114704

Xanthomatous Hypophysitis: A Novel Entity of Obscure Etiology.

Sanjeev S. Deodhare1, Juan M. Bilbao, Kalman Kovacs, Eva Horvath, P. Nomikos, M. Buchfelder, K. Reschke, H. Lehnert.   

Abstract

We report a case of xanthomatous hypophysitis, a recently described entity of obscure etiology affecting the pituitary gland, in a 43-yr-old woman, Histologically it is characterized by infiltration of the anterior pituitary by foamy histiocytes which are strongly immunoreactive for CD68 (histiocytic marker) and are immunonegative for 5100 and CD 1 a. Electron microscopy revealed histiocytes with abundant cytopasmic lipid droplets and membrane bound vacuoles. Fragments of intact anterior pituitary with preserved vascw lar and reticulin networks are seen. Xanthomatous hypophysitis resembles neoplasm on clinical and radiologic grounds.

Entities:  

Year:  1999        PMID： 12114704     DOI： 10.1007/bf02738885

Source DB:  PubMed          Journal:  Endocr Pathol        ISSN： 1046-3976            Impact factor:   3.943


  12 in total

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  14 in total

Review 1.  [Hypophysitis : Types and differential diagnosis].

Authors:  W Saeger
Journal:  Pathologe       Date:  2016-05       Impact factor: 1.011

2.  Xanthogranulomatous hypophysitis mimicking a pituitary neoplasm.

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3.  Xanthomatous Hypophysitis Is Associated with Ruptured Rathke's Cleft Cyst.

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4.  Hypophysitis Secondary to Cytotoxic T-Lymphocyte-Associated Protein 4 Blockade: Insights into Pathogenesis from an Autopsy Series.

Authors:  Patrizio Caturegli; Giulia Di Dalmazi; Martina Lombardi; Federica Grosso; H Benjamin Larman; Tatianna Larman; Giacomo Taverna; Mirco Cosottini; Isabella Lupi
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Authors:  Ferdinando Caranci; Giuseppe Leone; Andrea Ponsiglione; Massimo Muto; Fabio Tortora; Mario Muto; Sossio Cirillo; Luca Brunese; Alfonso Cerase
Journal:  Radiol Med       Date:  2019-12-20       Impact factor: 3.469

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10.  Xanthomatous hypophysitis associated with autoimmune disease in an elderly patient: A rare case report.

Authors:  Masahiro Oishi; Yasuhiko Hayashi; Issei Fukui; Daisuke Kita; Tadao Miyamori; Mitsutoshi Nakada
Journal:  Surg Neurol Int       Date:  2016-07-07
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