Literature DB >> 17912410

An esterase-activated magnetic resonance contrast agent.

Marco Giardiello1, Mark P Lowe, Mauro Botta.   

Abstract

A Gd(III) complex bearing pendant acetoxymethyl esters is activated on exposure to porcine liver esterase; the 84% increase in relaxivity is a result of suppression of HCO(3)(-)/CO(3)(2-) binding by the resulting negative charge.

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Year:  2007        PMID： 17912410     DOI： 10.1039/b711989e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  14 in total

1.  Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent.

Authors:  Keith W MacRenaris; Zhidong Ma; Ruby L Krueger; Christiane E Carney; Thomas J Meade
Journal:  Bioconjug Chem       Date:  2016-01-06       Impact factor: 4.774

Review 2.  Application of metal coordination chemistry to explore and manipulate cell biology.

Authors:  Kathryn L Haas; Katherine J Franz
Journal:  Chem Rev       Date:  2009-10       Impact factor: 60.622

3.  Gadolinium-based MRI contrast agent for the detection of tyrosinase.

Authors:  Hyewon Seo; Heather A Clark
Journal:  Analyst       Date:  2020-02-17       Impact factor: 4.616

4.  Molecular Magnetic Resonance Imaging with Gd(III)-Based Contrast Agents: Challenges and Key Advances.

Authors:  Hao Li; Thomas J Meade
Journal:  J Am Chem Soc       Date:  2019-10-17       Impact factor: 15.419

Review 5.  A review of responsive MRI contrast agents: 2005-2014.

Authors:  Dina V Hingorani; Adam S Bernstein; Mark D Pagel
Journal:  Contrast Media Mol Imaging       Date:  2014-10-29       Impact factor: 3.161

6.  Optical imaging of targeted β-galactosidase in brain tumors to detect EGFR levels.

Authors:  Ann-Marie Broome; Gopal Ramamurthy; Kari Lavik; Alexander Liggett; Ian Kinstlinger; James Basilion
Journal:  Bioconjug Chem       Date:  2015-03-30       Impact factor: 4.774

Review 7.  Environmentally responsive MRI contrast agents.

Authors:  Gemma-Louise Davies; Iris Kramberger; Jason J Davis
Journal:  Chem Commun (Camb)       Date:  2013-10-28       Impact factor: 6.222

Review 8.  Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers.

Authors:  Jessica Wahsner; Eric M Gale; Aurora Rodríguez-Rodríguez; Peter Caravan
Journal:  Chem Rev       Date:  2018-10-16       Impact factor: 60.622

Review 9.  Detecting enzyme activities with exogenous MRI contrast agents.

Authors:  Dina V Hingorani; Byunghee Yoo; Adam S Bernstein; Mark D Pagel
Journal:  Chemistry       Date:  2014-07-02       Impact factor: 5.236

10.  Effect of Magnetic Coupling on Water Proton Relaxivity in a Series of Transition Metal GdIII Complexes.

Authors:  Laura M Lilley; Kang Du; Matthew D Krzyaniak; Giacomo Parigi; Claudio Luchinat; T David Harris; Thomas J Meade
Journal:  Inorg Chem       Date:  2018-05-01       Impact factor: 5.165
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