Literature DB >> 17910461

A stereoselective intramolecular halo-etherification of chiral enamides in the synthesis of halogenated cyclic ethers.

Changhong Ko1, Richard P Hsung, Ziyad F Al-Rashid, John B Feltenberger, Ting Lu, Jin-Haek Yang, Yonggang Wei, Craig A Zificsak.   

Abstract

A stereoselective halo-etherification of chiral enamides is described here. This work provides an approach to halogen containing cyclic ethers and reveals further mechanistic insights to the chemistry of chiral enamides.

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Year:  2007        PMID: 17910461      PMCID: PMC3369430          DOI: 10.1021/ol701768n

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  26 in total

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