Literature DB >> 17909877

Genetic studies of diabetes following the advent of the genome-wide association study: where do we go from here?

T M Frayling1, M I McCarthy.   

Abstract

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Year:  2007        PMID： 17909877     DOI： 10.1007/s00125-007-0825-7

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  18 in total

1.  Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.

Authors:  Julius Gudmundsson; Patrick Sulem; Valgerdur Steinthorsdottir; Jon T Bergthorsson; Gudmar Thorleifsson; Andrei Manolescu; Thorunn Rafnar; Daniel Gudbjartsson; Bjarni A Agnarsson; Adam Baker; Asgeir Sigurdsson; Kristrun R Benediktsdottir; Margret Jakobsdottir; Thorarinn Blondal; Simon N Stacey; Agnar Helgason; Steinunn Gunnarsdottir; Adalheidur Olafsdottir; Kari T Kristinsson; Birgitta Birgisdottir; Shyamali Ghosh; Steinunn Thorlacius; Dana Magnusdottir; Gerdur Stefansdottir; Kristleifur Kristjansson; Yu Bagger; Robert L Wilensky; Muredach P Reilly; Andrew D Morris; Charlotte H Kimber; Adebowale Adeyemo; Yuanxiu Chen; Jie Zhou; Wing-Yee So; Peter C Y Tong; Maggie C Y Ng; Torben Hansen; Gitte Andersen; Knut Borch-Johnsen; Torben Jorgensen; Alejandro Tres; Fernando Fuertes; Manuel Ruiz-Echarri; Laura Asin; Berta Saez; Erica van Boven; Siem Klaver; Dorine W Swinkels; Katja K Aben; Theresa Graif; John Cashy; Brian K Suarez; Onco van Vierssen Trip; Michael L Frigge; Carole Ober; Marten H Hofker; Cisca Wijmenga; Claus Christiansen; Daniel J Rader; Colin N A Palmer; Charles Rotimi; Juliana C N Chan; Oluf Pedersen; Gunnar Sigurdsson; Rafn Benediktsson; Eirikur Jonsson; Gudmundur V Einarsson; Jose I Mayordomo; William J Catalona; Lambertus A Kiemeney; Rosa B Barkardottir; Jeffrey R Gulcher; Unnur Thorsteinsdottir; Augustine Kong; Kari Stefansson
Journal:  Nat Genet       Date:  2007-07-01       Impact factor: 38.330

2.  Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

Authors:  Stefano Romeo; Len A Pennacchio; Yunxin Fu; Eric Boerwinkle; Anne Tybjaerg-Hansen; Helen H Hobbs; Jonathan C Cohen
Journal:  Nat Genet       Date:  2007-02-25       Impact factor: 38.330

3.  The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes.

Authors:  Eva-Maria D Nielsen; Lars Hansen; Bendix Carstensen; Søren M Echwald; Thomas Drivsholm; Charlotte Glümer; Birger Thorsteinsson; Knut Borch-Johnsen; Torben Hansen; Oluf Pedersen
Journal:  Diabetes       Date:  2003-02       Impact factor: 9.461

4.  Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.

Authors:  Anna L Gloyn; Michael N Weedon; Katharine R Owen; Martina J Turner; Bridget A Knight; Graham Hitman; Mark Walker; Jonathan C Levy; Mike Sampson; Stephanie Halford; Mark I McCarthy; Andrew T Hattersley; Timothy M Frayling
Journal:  Diabetes       Date:  2003-02       Impact factor: 9.461

5.  Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

Authors:  Richa Saxena; Benjamin F Voight; Valeriya Lyssenko; Noël P Burtt; Paul I W de Bakker; Hong Chen; Jeffrey J Roix; Sekar Kathiresan; Joel N Hirschhorn; Mark J Daly; Thomas E Hughes; Leif Groop; David Altshuler; Peter Almgren; Jose C Florez; Joanne Meyer; Kristin Ardlie; Kristina Bengtsson Boström; Bo Isomaa; Guillaume Lettre; Ulf Lindblad; Helen N Lyon; Olle Melander; Christopher Newton-Cheh; Peter Nilsson; Marju Orho-Melander; Lennart Råstam; Elizabeth K Speliotes; Marja-Riitta Taskinen; Tiinamaija Tuomi; Candace Guiducci; Anna Berglund; Joyce Carlson; Lauren Gianniny; Rachel Hackett; Liselotte Hall; Johan Holmkvist; Esa Laurila; Marketa Sjögren; Maria Sterner; Aarti Surti; Margareta Svensson; Malin Svensson; Ryan Tewhey; Brendan Blumenstiel; Melissa Parkin; Matthew Defelice; Rachel Barry; Wendy Brodeur; Jody Camarata; Nancy Chia; Mary Fava; John Gibbons; Bob Handsaker; Claire Healy; Kieu Nguyen; Casey Gates; Carrie Sougnez; Diane Gage; Marcia Nizzari; Stacey B Gabriel; Gung-Wei Chirn; Qicheng Ma; Hemang Parikh; Delwood Richardson; Darrell Ricke; Shaun Purcell
Journal:  Science       Date:  2007-04-26       Impact factor: 47.728

6.  A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.

Authors:  Timothy M Frayling; Nicholas J Timpson; Michael N Weedon; Eleftheria Zeggini; Rachel M Freathy; Cecilia M Lindgren; John R B Perry; Katherine S Elliott; Hana Lango; Nigel W Rayner; Beverley Shields; Lorna W Harries; Jeffrey C Barrett; Sian Ellard; Christopher J Groves; Bridget Knight; Ann-Marie Patch; Andrew R Ness; Shah Ebrahim; Debbie A Lawlor; Susan M Ring; Yoav Ben-Shlomo; Marjo-Riitta Jarvelin; Ulla Sovio; Amanda J Bennett; David Melzer; Luigi Ferrucci; Ruth J F Loos; Inês Barroso; Nicholas J Wareham; Fredrik Karpe; Katharine R Owen; Lon R Cardon; Mark Walker; Graham A Hitman; Colin N A Palmer; Alex S F Doney; Andrew D Morris; George Davey Smith; Andrew T Hattersley; Mark I McCarthy
Journal:  Science       Date:  2007-04-12       Impact factor: 47.728

7.  A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

Authors:  Laura J Scott; Karen L Mohlke; Lori L Bonnycastle; Cristen J Willer; Yun Li; William L Duren; Michael R Erdos; Heather M Stringham; Peter S Chines; Anne U Jackson; Ludmila Prokunina-Olsson; Chia-Jen Ding; Amy J Swift; Narisu Narisu; Tianle Hu; Randall Pruim; Rui Xiao; Xiao-Yi Li; Karen N Conneely; Nancy L Riebow; Andrew G Sprau; Maurine Tong; Peggy P White; Kurt N Hetrick; Michael W Barnhart; Craig W Bark; Janet L Goldstein; Lee Watkins; Fang Xiang; Jouko Saramies; Thomas A Buchanan; Richard M Watanabe; Timo T Valle; Leena Kinnunen; Gonçalo R Abecasis; Elizabeth W Pugh; Kimberly F Doheny; Richard N Bergman; Jaakko Tuomilehto; Francis S Collins; Michael Boehnke
Journal:  Science       Date:  2007-04-26       Impact factor: 47.728

8.  Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.

Authors:  Wendy Winckler; Michael N Weedon; Robert R Graham; Steven A McCarroll; Shaun Purcell; Peter Almgren; Tiinamaija Tuomi; Daniel Gaudet; Kristina Bengtsson Boström; Mark Walker; Graham Hitman; Andrew T Hattersley; Mark I McCarthy; Kristin G Ardlie; Joel N Hirschhorn; Mark J Daly; Timothy M Frayling; Leif Groop; David Altshuler
Journal:  Diabetes       Date:  2007-03       Impact factor: 9.461

9.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

Authors: 
Journal:  Nature       Date:  2007-06-07       Impact factor: 49.962

10.  Common variants in WFS1 confer risk of type 2 diabetes.

Authors:  Manjinder S Sandhu; Michael N Weedon; Katherine A Fawcett; Jon Wasson; Sally L Debenham; Allan Daly; Hana Lango; Timothy M Frayling; Rosalind J Neumann; Richard Sherva; Ilana Blech; Paul D Pharoah; Colin N A Palmer; Charlotte Kimber; Roger Tavendale; Andrew D Morris; Mark I McCarthy; Mark Walker; Graham Hitman; Benjamin Glaser; M Alan Permutt; Andrew T Hattersley; Nicholas J Wareham; Inês Barroso
Journal:  Nat Genet       Date:  2007-07-01       Impact factor: 38.330
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  9 in total

Review 1.  The HapMap and genome-wide association studies in diagnosis and therapy.

Authors:  Teri A Manolio; Francis S Collins
Journal:  Annu Rev Med       Date:  2009       Impact factor: 13.739

Review 2.  A HapMap harvest of insights into the genetics of common disease.

Authors:  Teri A Manolio; Lisa D Brooks; Francis S Collins
Journal:  J Clin Invest       Date:  2008-05       Impact factor: 14.808

3.  Absence of association between specific common variants of the obesity-related FTO gene and psychological and behavioral eating disorder phenotypes.

Authors:  Charles R Jonassaint; Jin Peng Szatkiewicz; Cynthia M Bulik; Laura M Thornton; Cinnamon Bloss; Wade H Berrettini; Walter H Kaye; Andrew W Bergen; Pierre Magistretti; Michael Strober; Pamela K Keel; Harry Brandt; Steve Crawford; Scott Crow; Manfred M Fichter; David Goldman; Katherine A Halmi; Craig Johnson; Allan S Kaplan; Kelly L Klump; Maria La Via; James E Mitchell; Alessandro Rotondo; Janet Treasure; D Blake Woodside
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2011-03-22       Impact factor: 3.568

4.  Microarray analysis of multiple candidate genes and associated plasma proteins for nephropathy secondary to type 2 diabetes among Chinese individuals.

Authors:  S C Lim; J J Liu; H Q Low; N G Morgenthaler; Y Li; L Y Yeoh; Y S Wu; S K Goh; C Y Chionh; S H Tan; Y C Kon; P C Soon; Y M Bee; T Subramaniam; C F Sum; K S Chia
Journal:  Diabetologia       Date:  2009-05-05       Impact factor: 10.122

Review 5.  The Impact of obesity and diabetes mellitus on pancreatic cancer: Molecular mechanisms and clinical perspectives.

Authors:  Bao Quoc Lam; Sushant K Shrivastava; Anju Shrivastava; Sharmila Shankar; Rakesh K Srivastava
Journal:  J Cell Mol Med       Date:  2020-05-26       Impact factor: 5.310

6.  HNF1A gene polymorphisms and cardiovascular risk factors in individuals with late-onset autosomal dominant diabetes: a cross-sectional study.

Authors:  Fernando M A Giuffrida; Gilberto K Furuzawa; Teresa S Kasamatsu; Marcos M Oliveira; Andre F Reis; Sergio A Dib
Journal:  Cardiovasc Diabetol       Date:  2009-06-02       Impact factor: 9.951

7.  Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.

Authors:  Tina Rönn; Pernille Poulsen; Tiinamaija Tuomi; Bo Isomaa; Leif Groop; Allan Vaag; Charlotte Ling
Journal:  PLoS One       Date:  2009-03-10       Impact factor: 3.240

8.  Functional and genetic analysis in type 2 diabetes of liver X receptor alleles--a cohort study.

Authors:  Ingrid Dahlman; Maria Nilsson; Harvest F Gu; Cecile Lecoeur; Suad Efendic; Claes G Ostenson; Kerstin Brismar; Jan-Ake Gustafsson; Philippe Froguel; Martine Vaxillaire; Karin Dahlman-Wright; Knut R Steffensen
Journal:  BMC Med Genet       Date:  2009-03-17       Impact factor: 2.103

9.  Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Authors:  Fumihiko Takeuchi; Masakuni Serizawa; Ken Yamamoto; Tomomi Fujisawa; Eitaro Nakashima; Keizo Ohnaka; Hiroshi Ikegami; Takao Sugiyama; Tomohiro Katsuya; Makoto Miyagishi; Naoki Nakashima; Hajime Nawata; Jiro Nakamura; Suminori Kono; Ryoichi Takayanagi; Norihiro Kato
Journal:  Diabetes       Date:  2009-04-28       Impact factor: 9.461
  9 in total

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