OBJECTIVES: To assess the relationship between bladder pressure (BP) and pelvic floor muscle activity during coughing in women with stress urinary incontinence (SUI). METHODS: External anal sphincter integrated electromyographic activity (EAS-EMGi) was recorded in 21 women using pregelled surface electrodes. The relationship between BP and EAS-EMGi activity was assessed during four successive coughs at 0, 200, and 400 mL of filling. We also compared this relationship in 6 women presenting with SUI and 4 continent women. RESULTS: Among the considered models, a sigmoid relationship between EAS-EMGi and BP best described the data: EMGi = exp[a x (BP - b)]/(1 + exp[a x (BP - b)]). This relationship between EAS-EMGi and BP was significantly altered in women presenting with SUI (P <0.0001). CONCLUSIONS: Women with SUI exhibited an altered pattern of the pelvic floor muscle response during successive coughing efforts. The lack of this modulation of pelvic floor muscle response to stress might be one of the pathophysiologic factors of SUI.
OBJECTIVES: To assess the relationship between bladder pressure (BP) and pelvic floor muscle activity during coughing in women with stress urinary incontinence (SUI). METHODS: External anal sphincter integrated electromyographic activity (EAS-EMGi) was recorded in 21 women using pregelled surface electrodes. The relationship between BP and EAS-EMGi activity was assessed during four successive coughs at 0, 200, and 400 mL of filling. We also compared this relationship in 6 women presenting with SUI and 4 continent women. RESULTS: Among the considered models, a sigmoid relationship between EAS-EMGi and BP best described the data: EMGi = exp[a x (BP - b)]/(1 + exp[a x (BP - b)]). This relationship between EAS-EMGi and BP was significantly altered in women presenting with SUI (P <0.0001). CONCLUSIONS:Women with SUI exhibited an altered pattern of the pelvic floor muscle response during successive coughing efforts. The lack of this modulation of pelvic floor muscle response to stress might be one of the pathophysiologic factors of SUI.
Authors: Ruth C Lovegrove Jones; Qiyu Peng; Maria Stokes; Victor F Humphrey; Christopher Payne; Christos E Constantinou Journal: Eur Urol Date: 2009-06-21 Impact factor: 20.096
Authors: L Elaine Waetjen; Jingjing Ye; Wen-Ying Feng; Wesley O Johnson; Gail A Greendale; Carolyn M Sampselle; Barbara Sternfield; Siobàn D Harlow; Ellen B Gold Journal: Obstet Gynecol Date: 2009-11 Impact factor: 7.661
Authors: Margarita Martínez-Gómez; Mario I Romero-Ortega; Ana G Hernandez-Reynoso; Dora L Corona-Quintanilla; Kenia López-García; Ana A Horbovetz; Francisco Castelán; Philippe Zimmern Journal: Sci Rep Date: 2021-05-19 Impact factor: 4.379