| Literature DB >> 17901924 |
Jill T Jesurum1, Cindy J Fuller, Carles A Velez, Merrill P Spencer, Kimberly A Krabill, William H Likosky, William A Gray, John V Olsen, Mark Reisman.
Abstract
The objective of the study was to assess differences in proportion of large right-to-left shunt (RLS) and atrial septal characteristics between migraineurs and non-migraineurs referred for transcatheter closure of patent foramen ovale (PF0). This retrospective study took place in a large metropolitan medical centre. The patients were migraineurs with aura (n=52), migraineurs without aura (n=19) and non-migraineurs (n=149). RLS was evaluated before closure using bilateral power m-mode transcranial Doppler at rest and after calibrated, sustained Valsalva manoeuvre, and graded with a validated 0-5 scale. Intracardiac echocardiography was used to assess atrial septal characteristics. Migraineurs had a higher proportion of large RLS (Grade IV or V) than nonmigraineurs at rest and after calibrated Valsalva (rest, p=0.04; Valsalva, p=0.01). Atrial septal characteristics were similar between groups. Migraine is associated with larger RLS at rest and strain; however migraine status does not predict PFO characteristics.Entities:
Mesh：
Year: 2007 PMID： 17901924 PMCID： PMC3451677 DOI： 10.1007/s10194-007-0396-5
Source DB: PubMed Journal: J Headache Pain ISSN： 1129-2369 Impact factor: 7.277