Literature DB >> 17898898

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics.

Stefano Donadio1, Paolo Monciardini, Margherita Sosio.   

Abstract

A total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of genes encoding modular polyketide synthases (PKS) and nonribosomal peptide synthetases (NRPS). We report on the distribution of these systems in different bacterial taxa and, whenever known, the metabolites they synthesize. We also highlight, in the different bacterial lineages, the PKS and NRPS genes and, whenever known, the corresponding products.

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Year:  2007        PMID: 17898898     DOI: 10.1039/b514050c

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN: 0265-0568            Impact factor:   13.423


  110 in total

1.  Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

Authors:  Jun Fu; Xiaoying Bian; Shengbaio Hu; Hailong Wang; Fan Huang; Philipp M Seibert; Alberto Plaza; Liqiu Xia; Rolf Müller; A Francis Stewart; Youming Zhang
Journal:  Nat Biotechnol       Date:  2012-05       Impact factor: 54.908

2.  Culturable endophytes of medicinal plants and the genetic basis for their bioactivity.

Authors:  Kristin I Miller; Chen Qing; Daniel Man-Yuen Sze; Basil D Roufogalis; Brett A Neilan
Journal:  Microb Ecol       Date:  2012-03-21       Impact factor: 4.552

3.  A novel docking domain interface model predicting recombination between homoeologous modular biosynthetic gene clusters.

Authors:  Antonio Starcevic; Janko Diminic; Jurica Zucko; Mouhsine Elbekali; Tobias Schlosser; Mohamed Lisfi; Ana Vukelic; Paul F Long; Daslav Hranueli; John Cullum
Journal:  J Ind Microbiol Biotechnol       Date:  2010-11-24       Impact factor: 3.346

Review 4.  Current approaches to exploit actinomycetes as a source of novel natural products.

Authors:  Olga Genilloud; Ignacio González; Oscar Salazar; Jesus Martín; José Rubén Tormo; Francisca Vicente
Journal:  J Ind Microbiol Biotechnol       Date:  2010-10-08       Impact factor: 3.346

5.  Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses.

Authors:  Daniel W Udwary; Erin A Gontang; Adam C Jones; Carla S Jones; Andrew W Schultz; Jaclyn M Winter; Jane Y Yang; Nicholas Beauchemin; Todd L Capson; Benjamin R Clark; Eduardo Esquenazi; Alessandra S Eustáquio; Kelle Freel; Lena Gerwick; William H Gerwick; David Gonzalez; Wei-Ting Liu; Karla L Malloy; Katherine N Maloney; Markus Nett; Joshawna K Nunnery; Kevin Penn; Alejandra Prieto-Davo; Thomas L Simmons; Sara Weitz; Micheal C Wilson; Louis S Tisa; Pieter C Dorrestein; Bradley S Moore
Journal:  Appl Environ Microbiol       Date:  2011-04-15       Impact factor: 4.792

Review 6.  How nature morphs peptide scaffolds into antibiotics.

Authors:  Elizabeth M Nolan; Christopher T Walsh
Journal:  Chembiochem       Date:  2009-01-05       Impact factor: 3.164

7.  Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from Irish waters.

Authors:  Jonathan Kennedy; Paul Baker; Clare Piper; Paul D Cotter; Marcella Walsh; Marlies J Mooij; Marie B Bourke; Mary C Rea; Paula M O'Connor; R Paul Ross; Colin Hill; Fergal O'Gara; Julian R Marchesi; Alan D W Dobson
Journal:  Mar Biotechnol (NY)       Date:  2008-10-25       Impact factor: 3.619

8.  MS/MS networking guided analysis of molecule and gene cluster families.

Authors:  Don Duy Nguyen; Cheng-Hsuan Wu; Wilna J Moree; Anne Lamsa; Marnix H Medema; Xiling Zhao; Ronnie G Gavilan; Marystella Aparicio; Librada Atencio; Chanaye Jackson; Javier Ballesteros; Joel Sanchez; Jeramie D Watrous; Vanessa V Phelan; Corine van de Wiel; Roland D Kersten; Samina Mehnaz; René De Mot; Elizabeth A Shank; Pep Charusanti; Harish Nagarajan; Brendan M Duggan; Bradley S Moore; Nuno Bandeira; Bernhard Ø Palsson; Kit Pogliano; Marcelino Gutiérrez; Pieter C Dorrestein
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-24       Impact factor: 11.205

9.  MbtH homology codes to identify gifted microbes for genome mining.

Authors:  Richard H Baltz
Journal:  J Ind Microbiol Biotechnol       Date:  2013-11-07       Impact factor: 3.346

10.  Identification of a polyketide synthase coding sequence specific for anatoxin-a-producing Oscillatoria cyanobacteria.

Authors:  Sabrina Cadel-Six; Isabelle Iteman; Caroline Peyraud-Thomas; Stéphane Mann; Olivier Ploux; Annick Méjean
Journal:  Appl Environ Microbiol       Date:  2009-05-15       Impact factor: 4.792

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