Literature DB >> 17890844

RamB is an activator of the pyruvate dehydrogenase complex subunit E1p gene in Corynebacterium glutamicum.

Bastian Blombach1, Annette Cramer, Bernhard J Eikmanns, Mark Schreiner.   

Abstract

In Corynebacterium glutamicum, the transcriptional regulator RamB negatively controls the expression of genes involved in acetate metabolism. Here we show that during growth in media containing glucose and in complex medium without glucose RamB activates expression of the aceE gene, encoding the E1p subunit of the pyruvate dehydrogenase complex. Thus, RamB functions both as repressor and as activator in C. glutamicum. Copyright 2007 S. Karger AG, Basel.

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Year:  2007        PMID： 17890844     DOI： 10.1159/000108782

Source DB:  PubMed          Journal:  J Mol Microbiol Biotechnol        ISSN： 1464-1801


  7 in total

1.  Rapid functional screening of Streptomyces coelicolor regulators by use of a pH indicator and application to the MarR-like regulator AbsC.

Authors:  Yung-Hun Yang; Eunjung Song; Bo-Rahm Lee; Eun-jung Kim; Sung-Hee Park; Yun-Gon Kim; Chang-Soo Lee; Byung-Gee Kim
Journal:  Appl Environ Microbiol       Date:  2010-04-09       Impact factor: 4.792

2.  Genome-wide identification of in vivo binding sites of GlxR, a cyclic AMP receptor protein-type regulator in Corynebacterium glutamicum.

Authors:  Koichi Toyoda; Haruhiko Teramoto; Masayuki Inui; Hideaki Yukawa
Journal:  J Bacteriol       Date:  2011-06-10       Impact factor: 3.490

3.  Platform engineering of Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate.

Authors:  Jens Buchholz; Andreas Schwentner; Britta Brunnenkan; Christina Gabris; Simon Grimm; Robert Gerstmeir; Ralf Takors; Bernhard J Eikmanns; Bastian Blombach
Journal:  Appl Environ Microbiol       Date:  2013-07-08       Impact factor: 4.792

4.  Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex.

Authors:  Eduardo M Bruch; Pierre Vilela; Lu Yang; Alexandra Boyko; Norik Lexa-Sapart; Bertrand Raynal; Pedro M Alzari; Marco Bellinzoni
Journal:  Proc Natl Acad Sci U S A       Date:  2021-11-30       Impact factor: 11.205

5.  Role of the transcriptional regulator RamB (Rv0465c) in the control of the glyoxylate cycle in Mycobacterium tuberculosis.

Authors:  Julia C Micklinghoff; Katrin J Breitinger; Mascha Schmidt; Robert Geffers; Bernhard J Eikmanns; Franz-Christoph Bange
Journal:  J Bacteriol       Date:  2009-09-18       Impact factor: 3.490

6.  The global repressor SugR controls expression of genes of glycolysis and of the L-lactate dehydrogenase LdhA in Corynebacterium glutamicum.

Authors:  Verena Engels; Steffen N Lindner; Volker F Wendisch
Journal:  J Bacteriol       Date:  2008-10-10       Impact factor: 3.490

7.  Regulation of the pstSCAB operon in Corynebacterium glutamicum by the regulator of acetate metabolism RamB.

Authors:  Ulrike Sorger-Herrmann; Hironori Taniguchi; Volker F Wendisch
Journal:  BMC Microbiol       Date:  2015-05-29       Impact factor: 3.605
  7 in total

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