Michael Vogeser1, Stefan Lorenzl. 1. Institute of Clinical Chemistry, Hospital of the University of Munich, Marchioninistr. 15, D-81377 Munich, Germany. Michael.Vogeser@med.uni-muenchen.de
Abstract
OBJECTIVES: To study the agreement of serum cobalamin results obtained with three different widely used analyzers. DESIGN AND METHODS: Comparative measurement of 100 serum samples was performed using the Abbott Architect, the Bayer Centaur, and the Roche Elecsys 2010 analyzer. RESULTS: Relatively close numeric correlation of the results was found with Pearson's r>0.95 for all three comparisons; however, the mean concentration of the highest reading and the lowest reading method differed by 16%. CONCLUSIONS: Relatively good agreement of results from three automated serum cobalamin assays was observed.
OBJECTIVES: To study the agreement of serum cobalamin results obtained with three different widely used analyzers. DESIGN AND METHODS: Comparative measurement of 100 serum samples was performed using the Abbott Architect, the Bayer Centaur, and the Roche Elecsys 2010 analyzer. RESULTS: Relatively close numeric correlation of the results was found with Pearson's r>0.95 for all three comparisons; however, the mean concentration of the highest reading and the lowest reading method differed by 16%. CONCLUSIONS: Relatively good agreement of results from three automated serum cobalamin assays was observed.
Authors: Jose L Flores-Guerrero; Isidor Minovic; Dion Groothof; Eke G Gruppen; Ineke J Riphagen; Jenny Kootstra-Ros; Anneke Muller Kobold; Eelko Hak; Gerjan Navis; Ron T Gansevoort; Martin H de Borst; Robin P F Dullaart; Stephan J L Bakker Journal: JAMA Netw Open Date: 2020-01-03