Literature DB >> 17889084

Glucose-6-phosphate dehydrogenase deficiency: another risk factor for necrotizing enterocolitis?

David L Schutzman1, Rachel Porat.   

Abstract

We recently observed several babies in our neonatal intensive care unit (NICU) with necrotizing enterocolitis (NEC) who were subsequently found to have glucose-6-phosphate dehydrogenase (G6PD) deficiency. The aim of this study was to explore the association of NEC and G6PD deficiency. G6PD deficiency was significantly higher (27.8%) in infants with NEC compared with the 5.3% prevalence among NICU admissions (odds ratio = 6.9; 95% confidence interval = 2 to 23.5). G6PD deficiency also was found to be a marker for more severe NEC. G6PD deficiency should be considered a risk factor for NEC.

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Year:  2007        PMID： 17889084     DOI： 10.1016/j.jpeds.2007.06.041

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  4 in total

1.  Do red cell transfusions increase the risk of necrotizing enterocolitis in premature infants?

Authors:  Cassandra D Josephson; Agnieszka Wesolowski; Gaobin Bao; Martha C Sola-Visner; Golde Dudell; Marta-Inés Castillejo; Beth H Shaz; Kirk A Easley; Christopher D Hillyer; Akhil Maheshwari
Journal:  J Pediatr       Date:  2010-07-21       Impact factor: 4.406

2.  Current Understanding of Transfusion-associated Necrotizing Enterocolitis: Review of Clinical and Experimental Studies and a Call for More Definitive Evidence.

Authors:  Minesh Khashu; Christof Dame; Pascal M Lavoie; Isabelle G De Plaen; Parvesh M Garg; Venkatesh Sampath; Atul Malhotra; Michael D Caplan; Praveen Kumar; Pankaj B Agrawal; Giuseppe Buonocore; Robert D Christensen; Akhil Maheshwari
Journal:  Newborn (Clarksville)       Date:  2022-03-31

Review 3.  Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis.

Authors:  Akhil Maheshwari
Journal:  Clin Perinatol       Date:  2015-05-13       Impact factor: 3.430

4.  A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions.

Authors:  Krishnan MohanKumar; Kopperuncholan Namachivayam; Tanjing Song; Byeong Jake Cha; Andrea Slate; Jeanne E Hendrickson; Hua Pan; Samuel A Wickline; Joo-Yeun Oh; Rakesh P Patel; Ling He; Benjamin A Torres; Akhil Maheshwari
Journal:  Nat Commun       Date:  2019-08-02       Impact factor: 14.919
  4 in total

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