Literature DB >> 17888658

Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.

Martijn Verdoes1, Ulrik Hillaert, Bogdan I Florea, Myra Sae-Heng, Martijn D P Risseeuw, Dmitri V Filippov, Gijsbert A van der Marel, Herman S Overkleeft.   

Abstract

The synthesis of three acetylene functionalized BODIPY dyes is described. These dyes are used to fluorescently modify an azido functionalized epoxomicin analogue employing the Huisgen 1,3-dipolar cycloaddition, resulting in a panel of fluorescent epoxomicin derived proteasome probes.

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Year:  2007        PMID： 17888658     DOI： 10.1016/j.bmcl.2007.09.025

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  16 in total

1.  A panel of subunit-selective activity-based proteasome probes.

Authors:  Martijn Verdoes; Lianne I Willems; Wouter A van der Linden; Boudewijn A Duivenvoorden; Gijsbert A van der Marel; Bogdan I Florea; Alexei F Kisselev; Herman S Overkleeft
Journal:  Org Biomol Chem       Date:  2010-05-06       Impact factor: 3.876

2.  A bright approach to the immunoproteasome: development of LMP2/β1i-specific imaging probes.

Authors:  Kimberly Cornish Carmony; Do-Min Lee; Ying Wu; Na-Ra Lee; Marie Wehenkel; Jason Lee; Beilei Lei; Chang-Guo Zhan; Kyung-Bo Kim
Journal:  Bioorg Med Chem       Date:  2011-07-07       Impact factor: 3.641

3.  Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies.

Authors:  Jaime M Predmore; Ping Wang; Frank Davis; Sarah Bartolone; Margaret V Westfall; David B Dyke; Francis Pagani; Saul R Powell; Sharlene M Day
Journal:  Circulation       Date:  2010-02-16       Impact factor: 29.690

4.  Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites.

Authors:  Paul P Geurink; Nora Liu; Michiel P Spaans; Sondra L Downey; Adrianus M C H van den Nieuwendijk; Gijsbert A van der Marel; Alexei F Kisselev; Bogdan I Florea; Herman S Overkleeft
Journal:  J Med Chem       Date:  2010-03-11       Impact factor: 7.446

5.  Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases.

Authors:  Casper de Boer; Nicholas G S McGregor; Evert Peterse; Sybrin P Schröder; Bogdan I Florea; Jianbing Jiang; Jos Reijngoud; Arthur F J Ram; Gilles P van Wezel; Gijsbert A van der Marel; Jeroen D C Codée; Herman S Overkleeft; Gideon J Davies
Journal:  RSC Chem Biol       Date:  2020-07-28

6.  Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites.

Authors:  Paul P Geurink; Wouter A van der Linden; Anne C Mirabella; Nerea Gallastegui; Gerjan de Bruin; Annet E M Blom; Mathias J Voges; Elliot D Mock; Bogdan I Florea; Gijs A van der Marel; Christoph Driessen; Mario van der Stelt; Michael Groll; Herman S Overkleeft; Alexei F Kisselev
Journal:  J Med Chem       Date:  2013-01-28       Impact factor: 7.446

Review 7.  The chemistry and biology of mycolactones.

Authors:  Matthias Gehringer; Karl-Heinz Altmann
Journal:  Beilstein J Org Chem       Date:  2017-08-11       Impact factor: 2.883

Review 8.  Activity-based imaging probes of the proteasome.

Authors:  Kimberly Cornish Carmony; Kyung Bo Kim
Journal:  Cell Biochem Biophys       Date:  2013-09       Impact factor: 2.194

9.  De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.

Authors:  Yu Liu; Xin Zhang; Yun Lei Tan; Gira Bhabha; Damian C Ekiert; Yakov Kipnis; Sinisa Bjelic; David Baker; Jeffery W Kelly
Journal:  J Am Chem Soc       Date:  2014-09-11       Impact factor: 15.419

10.  Design, Synthesis and Characterization of a New Series of Fluorescent Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulators.

Authors:  Víctor Fernández-Dueñas; Mingcheng Qian; Josep Argerich; Carolina Amaral; Martijn D P Risseeuw; Serge Van Calenbergh; Francisco Ciruela
Journal:  Molecules       Date:  2020-03-27       Impact factor: 4.411
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