Literature DB >> 17887893

Pulsatile blood flow and gas exchange across a cylindrical fiber array.

Kit Yan Chan1, Hideki Fujioka, Ronald B Hirshl, Robert H Bartlett, James B Grotberg.   

Abstract

The pulsatile blood flow and gas transport of oxygen and carbon dioxide through a cylindrical array of microfibers are numerically simulated. Blood is modeled as a homogeneous Casson fluid, and hemoglobin molecules in blood are assumed to be in local equilibrium with oxygen and carbon dioxide. It is shown that flow pulsatility enhances gas transport and the amount of gas exchange is sensitive to the blood flow field across the fibers. The steady Sherwood number dependence on Reynolds number was shown to have a linear relation consistent with experimental findings. For most cases, an enhancement in gas transport is accompanied with an increase in flow resistance. Maximum local shear stress is provided as a possible indicator of thrombosis, and the computed shear stress is shown to be below the threshold value for thrombosis formation for all cases evaluated.

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Year:  2007        PMID: 17887893     DOI: 10.1115/1.2768105

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  3 in total

1.  Computational study of the blood flow in three types of 3D hollow fiber membrane bundles.

Authors:  Jiafeng Zhang; Xiaobing Chen; Jun Ding; Katharine H Fraser; M Ertan Taskin; Bartley P Griffith; Zhongjun J Wu
Journal:  J Biomech Eng       Date:  2013-12       Impact factor: 2.097

2.  An Investigation of Pulsatile Flow Past Two Cylinders as a Model of Blood Flow in an Artificial Lung.

Authors:  Yu-Chun Lin; Khalil M Khanafer; Robert H Bartlett; Ronald B Hirschl; Joseph L Bull
Journal:  Int J Heat Mass Transf       Date:  2011-07       Impact factor: 5.584

3.  Timing and size of flow impingement in a giant intracranial aneurysm at the internal carotid artery.

Authors:  Liang-Der Jou; Michel E Mawad
Journal:  Med Biol Eng Comput       Date:  2011-01-06       Impact factor: 2.602

  3 in total

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