| Literature DB >> 1787822 |
Abstract
The preponderance of gallstones in fertile women suggests that female sex hormones play a role in the pathogenesis of cholelithiasis. In a pilot study we found estrogen receptors and high concentrations of estrogen in gallbladders of persons who underwent cholecystectomy for cholelithiasis. This finding, as well as previous reports on estrogen receptors in diverse human tumors, support the hypothesis that estrogen influences the development of gallstone disease and gallbladder carcinoma.Entities:
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Year: 1991 PMID: 1787822 DOI: 10.1016/0306-9877(91)90145-o
Source DB: PubMed Journal: Med Hypotheses ISSN: 0306-9877 Impact factor: 1.538