Steven M Houser1. 1. MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA. shouser@metrohealth.org
Abstract
OBJECTIVES: To detail empty nose syndrome (ENS), an iatrogenic disorder characterized by a patent airway but a subjective sense of poor nasal breathing, and to explore repair options for patients with ENS. DESIGN: A case series of 8 patients with ENS detailing symptoms before and after submucosal implantation of acellular dermis. SETTING: Academic medical center. PATIENTS: Subjects who were evaluated for abnormal nasal breathing and determined to have ENS. Patients were diagnosed as having ENS if they described characteristic symptoms, had evidence of prior nasal turbinate surgery, and their symptoms improved after they underwent a cotton test. INTERVENTION: Acellular dermis was implanted submucosally to simulate missing turbinate tissue. MAIN OUTCOME MEASURES: Symptoms and symptom scores for the 20-item Sino-Nasal Outcome Test completed before and after the implantation were gathered. RESULTS: A statistically significant improvement in symptom scores for the Sino-Nasal Outcome Test was noted (P < or = .02). CONCLUSIONS: Careful assessment allows reconstructive surgery through submucosal implantation of acellular dermis. Symptoms of patients with ENS can improve with surgical therapy.
OBJECTIVES: To detail empty nose syndrome (ENS), an iatrogenic disorder characterized by a patent airway but a subjective sense of poor nasal breathing, and to explore repair options for patients with ENS. DESIGN: A case series of 8 patients with ENS detailing symptoms before and after submucosal implantation of acellular dermis. SETTING: Academic medical center. PATIENTS: Subjects who were evaluated for abnormal nasal breathing and determined to have ENS. Patients were diagnosed as having ENS if they described characteristic symptoms, had evidence of prior nasal turbinate surgery, and their symptoms improved after they underwent a cotton test. INTERVENTION: Acellular dermis was implanted submucosally to simulate missing turbinate tissue. MAIN OUTCOME MEASURES: Symptoms and symptom scores for the 20-item Sino-Nasal Outcome Test completed before and after the implantation were gathered. RESULTS: A statistically significant improvement in symptom scores for the Sino-Nasal Outcome Test was noted (P < or = .02). CONCLUSIONS: Careful assessment allows reconstructive surgery through submucosal implantation of acellular dermis. Symptoms of patients with ENS can improve with surgical therapy.
Authors: Sophie Anna Holak; Marek Wysocki; Nikolai Holak; Heinrich Holak Journal: Graefes Arch Clin Exp Ophthalmol Date: 2011-11-19 Impact factor: 3.117
Authors: Chengyu Li; Alexander A Farag; James Leach; Bhakthi Deshpande; Adam Jacobowitz; Kanghyun Kim; Bradley A Otto; Kai Zhao Journal: Laryngoscope Date: 2017-03-09 Impact factor: 3.325
Authors: Chengyu Li; Alexander A Farag; Guillermo Maza; Sam McGhee; Michael A Ciccone; Bhakthi Deshpande; Edmund A Pribitkin; Bradley A Otto; Kai Zhao Journal: Int Forum Allergy Rhinol Date: 2017-11-22 Impact factor: 3.858
Authors: Sarah K Wise; Sandra Y Lin; Elina Toskala; Richard R Orlandi; Cezmi A Akdis; Jeremiah A Alt; Antoine Azar; Fuad M Baroody; Claus Bachert; G Walter Canonica; Thomas Chacko; Cemal Cingi; Giorgio Ciprandi; Jacquelynne Corey; Linda S Cox; Peter Socrates Creticos; Adnan Custovic; Cecelia Damask; Adam DeConde; John M DelGaudio; Charles S Ebert; Jean Anderson Eloy; Carrie E Flanagan; Wytske J Fokkens; Christine Franzese; Jan Gosepath; Ashleigh Halderman; Robert G Hamilton; Hans Jürgen Hoffman; Jens M Hohlfeld; Steven M Houser; Peter H Hwang; Cristoforo Incorvaia; Deborah Jarvis; Ayesha N Khalid; Maritta Kilpeläinen; Todd T Kingdom; Helene Krouse; Desiree Larenas-Linnemann; Adrienne M Laury; Stella E Lee; Joshua M Levy; Amber U Luong; Bradley F Marple; Edward D McCoul; K Christopher McMains; Erik Melén; James W Mims; Gianna Moscato; Joaquim Mullol; Harold S Nelson; Monica Patadia; Ruby Pawankar; Oliver Pfaar; Michael P Platt; William Reisacher; Carmen Rondón; Luke Rudmik; Matthew Ryan; Joaquin Sastre; Rodney J Schlosser; Russell A Settipane; Hemant P Sharma; Aziz Sheikh; Timothy L Smith; Pongsakorn Tantilipikorn; Jody R Tversky; Maria C Veling; De Yun Wang; Marit Westman; Magnus Wickman; Mark Zacharek Journal: Int Forum Allergy Rhinol Date: 2018-02 Impact factor: 3.858