Literature DB >> 17872742

Omega-3 fatty acid supplementation during pregnancy: for mother, baby, or neither?

Gal Dubnov-Raz, Yaron Finkelstein, Gideon Koren.   

Abstract

QUESTION: Several pregnant patients have asked recently whether media reports of children's intelligence quotients' increasing with increased intake of essential fatty acids are meaningful enough to be worth the effort of supplementation. What advice should they be given? ANSWER: Existing evidence from interventional studies is sparse and conflicting and should not lead to supplementation with polyunsaturated fatty acids.

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Year:  2007        PMID: 17872742      PMCID: PMC1949164     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  19 in total

1.  Randomised clinical trials of fish oil supplementation in high risk pregnancies. Fish Oil Trials In Pregnancy (FOTIP) Team.

Authors:  S F Olsen; N J Secher; A Tabor; T Weber; J J Walker; C Gluud
Journal:  BJOG       Date:  2000-03       Impact factor: 6.531

2.  Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration.

Authors:  S F Olsen; J D Sørensen; N J Secher; M Hedegaard; T B Henriksen; H S Hansen; A Grant
Journal:  Lancet       Date:  1992-04-25       Impact factor: 79.321

Review 3.  Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation.

Authors:  M Makrides; R A Gibson
Journal:  Am J Clin Nutr       Date:  2000-01       Impact factor: 7.045

4.  A randomised double blind placebo controlled trial of fish oil in high risk pregnancy.

Authors:  J L Onwude; R J Lilford; H Hjartardottir; A Staines; D Tuffnell
Journal:  Br J Obstet Gynaecol       Date:  1995-02

5.  Effect of DHA-containing formula on growth of preterm infants to 59 weeks postmenstrual age.

Authors:  Alan S. Ryan; Michael B. Montalto; Sharon Groh-Wargo; Francis Mimouni; Joan Sentipal-Walerius; Jeanine Doyle; Joel S. Siegman; Alicia J. Thomas
Journal:  Am J Hum Biol       Date:  1999       Impact factor: 1.937

Review 6.  Perinatal supply and metabolism of long-chain polyunsaturated fatty acids: importance for the early development of the nervous system.

Authors:  Elvira Larque; Hans Demmelmair; Berthold Koletzko
Journal:  Ann N Y Acad Sci       Date:  2002-06       Impact factor: 5.691

7.  Essential fatty acid status in neonates after fish-oil supplementation during late pregnancy.

Authors:  A C van Houwelingen; J D Sørensen; G Hornstra; M M Simonis; J Boris; S F Olsen; N J Secher
Journal:  Br J Nutr       Date:  1995-11       Impact factor: 3.718

8.  First year growth of preterm infants fed standard compared to marine oil n-3 supplemented formula.

Authors:  S E Carlson; R J Cooke; S H Werkman; E A Tolley
Journal:  Lipids       Date:  1992-11       Impact factor: 1.880

9.  A randomized trial of docosahexaenoic acid supplementation during the third trimester of pregnancy.

Authors:  Cornelius M Smuts; Minzhao Huang; David Mundy; Terry Plasse; Stacey Major; Susan E Carlson
Journal:  Obstet Gynecol       Date:  2003-03       Impact factor: 7.661

10.  Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age.

Authors:  Ingrid B Helland; Lars Smith; Kristin Saarem; Ola D Saugstad; Christian A Drevon
Journal:  Pediatrics       Date:  2003-01       Impact factor: 7.124

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  7 in total

1.  Recommend omega-3 fatty acids in pregnancy?

Authors:  Gerry Schwalfenberg
Journal:  Can Fam Physician       Date:  2007-08       Impact factor: 3.275

Review 2.  Healthy fish consumption and reduced mercury exposure: counseling women in their reproductive years.

Authors:  Alan Abelsohn; Loren D Vanderlinden; Fran Scott; Josephine A Archbold; Tara L Brown
Journal:  Can Fam Physician       Date:  2011-01       Impact factor: 3.275

3.  Polyunsaturated fatty acids and fetal brain development.

Authors:  Gideon Koren
Journal:  Can Fam Physician       Date:  2015-01       Impact factor: 3.275

4.  Effects of ω-3 Fatty Acids and Catechins on Fatty Acid Synthase in the Prostate: A Randomized Controlled Trial.

Authors:  Zhenzhen Zhang; Mark Garzotto; Tomasz M Beer; Philippe Thuillier; Stephen Lieberman; Motomi Mori; Wesley A Stoller; Paige E Farris; Jackilen Shannon
Journal:  Nutr Cancer       Date:  2016-09-20       Impact factor: 2.900

5.  Interaction of diet and the masou salmon Δ5-desaturase transgene on Δ6-desaturase and stearoyl-CoA desaturase gene expression and N-3 fatty acid level in common carp (Cyprinus carpio).

Authors:  Qi Cheng; Baofeng Su; Zhenkui Qin; Chia-Chen Weng; Fang Yin; Yangen Zhou; Michael Fobes; Dayan A Perera; Mei Shang; Fabio Soller; Zhiyi Shi; Allen Davis; Rex A Dunham
Journal:  Transgenic Res       Date:  2014-07-11       Impact factor: 2.788

6.  The effects of maternal supplementation of polyunsaturated Fatty acids on visual, neurobehavioural, and developmental outcomes of the child: a systematic review of the randomized trials.

Authors:  Andrea Lo; Julianna Sienna; Eva Mamak; Nada Djokanovic; Carol Westall; Gideon Koren
Journal:  Obstet Gynecol Int       Date:  2012-01-18

7.  Sex Differences in Early Programming by Maternal High Fat Diet Induced-Obesity and Fish Oil Supplementation in Mice.

Authors:  Latha Ramalingam; Kalhara R Menikdiwela; Stephani Spainhour; Tochi Eboh; Naima Moustaid-Moussa
Journal:  Nutrients       Date:  2021-10-21       Impact factor: 5.717

  7 in total

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