Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.

Literature DB >> 17868168

Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors.

Arturo J Vegas¹, James E Bradner, Weiping Tang, Olivia M McPherson, Edward F Greenberg, Angela N Koehler, Stuart L Schreiber.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2007 PMID： 17868168 PMCID： PMC2790065 DOI： 10.1002/anie.200703198

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

× No keyword cloud information.

36 in total

Review 1. Deacetylase enzymes: biological functions and the use of small-molecule inhibitors.

Authors: Christina M Grozinger; Stuart L Schreiber
Journal: Chem Biol Date: 2002-01

2. Staudinger ligation: a new immobilization strategy for the preparation of small-molecule arrays.

Authors: Maja Köhn; Ron Wacker; Carsten Peters; Hendrik Schröder; Laurent Soulère; Rolf Breinbauer; Christof M Niemeyer; Herbert Waldmann
Journal: Angew Chem Int Ed Engl Date: 2003 Impact factor: 15.336

3. Analysis of small-molecule interactions using Biacore S51 technology.

Authors: David G Myszka
Journal: Anal Biochem Date: 2004-06-15 Impact factor: 3.365

Review 4. Chromatin modifications and their function.

Authors: Tony Kouzarides
Journal: Cell Date: 2007-02-23 Impact factor: 41.582

5. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation.

Authors: Stephen J Haggarty; Kathryn M Koeller; Jason C Wong; Christina M Grozinger; Stuart L Schreiber
Journal: Proc Natl Acad Sci U S A Date: 2003-04-03 Impact factor: 11.205

6. Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin.

Authors: S M Sternson; J C Wong; C M Grozinger; S L Schreiber
Journal: Org Lett Date: 2001-12-27 Impact factor: 6.005

Review 7. Histone deacetylases (HDACs): characterization of the classical HDAC family.

Authors: Annemieke J M de Ruijter; Albert H van Gennip; Huib N Caron; Stephan Kemp; André B P van Kuilenburg
Journal: Biochem J Date: 2003-03-15 Impact factor: 3.857

8. Structural biasing elements for in-cell histone deacetylase paralog selectivity.

Authors: Jason C Wong; Roger Hong; Stuart L Schreiber
Journal: J Am Chem Soc Date: 2003-05-14 Impact factor: 15.419

9. Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

Authors: Wm Kevin Kelly; Victoria M Richon; Owen O'Connor; Tracy Curley; Barbara MacGregor-Curtelli; William Tong; Mark Klang; Lawrence Schwartz; Stacie Richardson; Eddie Rosa; Marija Drobnjak; Carlos Cordon-Cordo; Judy H Chiao; Richard Rifkind; Paul A Marks; Howard Scher
Journal: Clin Cancer Res Date: 2003-09-01 Impact factor: 12.531

10. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease.

Authors: Emma Hockly; Victoria M Richon; Benjamin Woodman; Donna L Smith; Xianbo Zhou; Eddie Rosa; Kirupa Sathasivam; Shabnam Ghazi-Noori; Amarbirpal Mahal; Philip A S Lowden; Joan S Steffan; J Lawrence Marsh; Leslie M Thompson; Cathryn M Lewis; Paul A Marks; Gillian P Bates
Journal: Proc Natl Acad Sci U S A Date: 2003-02-07 Impact factor: 11.205

25 in total

Review 1. Small-molecule microarrays as tools in ligand discovery.

Authors: Arturo J Vegas; Jason H Fuller; Angela N Koehler
Journal: Chem Soc Rev Date: 2008-05-20 Impact factor: 54.564

2. Proteins from an unevolved library of de novo designed sequences bind a range of small molecules.

Authors: Izhack Cherny; Maria Korolev; Angela N Koehler; Michael H Hecht
Journal: ACS Synth Biol Date: 2012-04-02 Impact factor: 5.110

3. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.

Authors: Teru Hideshima; Jun Qi; Ronald M Paranal; Weiping Tang; Edward Greenberg; Nathan West; Meaghan E Colling; Guillermina Estiu; Ralph Mazitschek; Jennifer A Perry; Hiroto Ohguchi; Francesca Cottini; Naoya Mimura; Güllü Görgün; Yu-Tzu Tai; Paul G Richardson; Ruben D Carrasco; Olaf Wiest; Stuart L Schreiber; Kenneth C Anderson; James E Bradner
Journal: Proc Natl Acad Sci U S A Date: 2016-10-31 Impact factor: 11.205

4. Tag and Capture Flow Hydrogen Exchange Mass Spectrometry with a Fluorous-Immobilized Probe.

Authors: Sean R Marcsisin; Cary Liptak; Jason Marineau; James E Bradner; John R Engen
Journal: Anal Chem Date: 2015-05-29 Impact factor: 6.986

5. Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity.

Authors: Jermont Chen; Anne H Armstrong; Angela N Koehler; Michael H Hecht
Journal: J Am Chem Soc Date: 2010-11-09 Impact factor: 15.419