Literature DB >> 17867694

Convenient synthesis of highly functionalized pyrazolines via mild, photoactivated 1,3-dipolar cycloaddition.

Yizhong Wang1, Claudia I Rivera Vera, Qing Lin.   

Abstract

A mild, photoactivated 1,3-dipolar cycloaddition procedure was successfully developed for the synthesis of polysubstituted pyrazolines. This procedure involved the in situ generation of the reactive nitrile imine dipoles using a hand-held UV lamp at 302 nm, followed by spontaneous cycloaddition with a broad range of 1,3-dipolarophiles with excellent solvent compatibility, functional group tolerance, regioselectivity, and yield.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17867694     DOI: 10.1021/ol7017328

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  29 in total

Review 1.  Photo-Triggered Click Chemistry for Biological Applications.

Authors:  András Herner; Qing Lin
Journal:  Top Curr Chem (Cham)       Date:  2015-12-11

Review 2.  Bioorthogonal chemistry: recent progress and future directions.

Authors:  Reyna K V Lim; Qing Lin
Journal:  Chem Commun (Camb)       Date:  2010-01-21       Impact factor: 6.222

3.  Synthesis of macrocyclic tetrazoles for rapid photoinduced bioorthogonal 1,3-dipolar cycloaddition reactions.

Authors:  Zhipeng Yu; Reyna K V Lim; Qing Lin
Journal:  Chemistry       Date:  2010-12-03       Impact factor: 5.236

4.  Design and synthesis of laser-activatable tetrazoles for a fast and fluorogenic red-emitting 1,3-dipolar cycloaddition reaction.

Authors:  Peng An; Zhipeng Yu; Qing Lin
Journal:  Org Lett       Date:  2013-10-10       Impact factor: 6.005

Review 5.  Click chemistry in complex mixtures: bioorthogonal bioconjugation.

Authors:  Craig S McKay; M G Finn
Journal:  Chem Biol       Date:  2014-09-18

6.  Discovery of new photoactivatable diaryltetrazoles for photoclick chemistry via 'scaffold hopping'.

Authors:  Zhipeng Yu; Lok Yin Ho; Zhiyong Wang; Qing Lin
Journal:  Bioorg Med Chem Lett       Date:  2011-04-24       Impact factor: 2.823

7.  5-(Methylthio)tetrazoles as Versatile Synthons in the Stereoselective Synthesis of Polycyclic Pyrazolines via Photoinduced Intramolecular Nitrile Imine-Alkene 1,3-Dipolar Cycloaddition.

Authors:  Daniel Pla; Derek S Tan; David Y Gin
Journal:  Chem Sci       Date:  2014-06-01       Impact factor: 9.825

8.  Photoinducible Oncometabolite Detection.

Authors:  Rhushikesh A Kulkarni; Chloe A Briney; Daniel R Crooks; Sarah E Bergholtz; Chandrasekhar Mushti; Stephen J Lockett; Andrew N Lane; Teresa W-M Fan; Rolf E Swenson; W Marston Linehan; Jordan L Meier
Journal:  Chembiochem       Date:  2018-12-13       Impact factor: 3.164

9.  Direct observation of a photoinduced nonstabilized nitrile imine structure in the solid state.

Authors:  Shao-Liang Zheng; Yizhong Wang; Zhipeng Yu; Qing Lin; Philip Coppens
Journal:  J Am Chem Soc       Date:  2009-12-23       Impact factor: 15.419

10.  Novel Strategy for Preparing Dual-Modality Optical/PET Imaging Probes via Photo-Click Chemistry.

Authors:  Lingyi Sun; Jiule Ding; Wei Xing; Yongkang Gai; Jing Sheng; Dexing Zeng
Journal:  Bioconjug Chem       Date:  2016-04-27       Impact factor: 4.774

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.