Literature DB >> 17867547

Biosynthesis and biological activity of enniatins.

S Firáková1, B Proksa, M Sturdíkova.   

Abstract

Enniatins are N-methylated cyclohexadepsipeptides (CHDPs), composed of three units each of N-methylated branched-chain L-amino acid and D-2-hydroxy acid arranged in an alternate fashion. These low-molecular secondary metabolites are produced by Fusarium species, typical mycotoxin producing fungi. Enniatins are known for their ionophoric, phytotoxic and anthelmintic effect, antibiotic activity and recently their potent cytotoxic activity against cancer cell lines was shown. They act also as inhibitors of drug efflux pumps. Biosynthesis, biological activity, and the structural characteristics of these microbial metabolites were summarized in this review.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17867547

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  12 in total

1.  Comparative analysis of antimicrobial activities of valinomycin and cereulide, the Bacillus cereus emetic toxin.

Authors:  Marcel H Tempelaars; Susana Rodrigues; Tjakko Abee
Journal:  Appl Environ Microbiol       Date:  2011-02-25       Impact factor: 4.792

Review 2.  Revisiting the enniatins: a review of their isolation, biosynthesis, structure determination and biological activities.

Authors:  Arlene A Sy-Cordero; Cedric J Pearce; Nicholas H Oberlies
Journal:  J Antibiot (Tokyo)       Date:  2012-09-19       Impact factor: 2.649

3.  Mycotoxins produced by Fusarium species associated with annual legume pastures and 'sheep feed refusal disorders' in Western Australia.

Authors:  Diana C Tan; Gavin R Flematti; Emilio L Ghisalberti; Krishnapillai Sivasithamparam; Sukumar Chakraborty; Friday Obanor; Martin John Barbetti
Journal:  Mycotoxin Res       Date:  2011-01-12       Impact factor: 3.833

4.  The emerging Fusarium toxin enniatin B: in-vitro studies on its genotoxic potential and cytotoxicity in V79 cells in relation to other mycotoxins.

Authors:  Wolfram Föllmann; Claudia Behm; Gisela H Degen
Journal:  Mycotoxin Res       Date:  2008-12-17       Impact factor: 3.833

5.  Engineering of Aspergillus niger for the production of secondary metabolites.

Authors:  Lennart Richter; Franziska Wanka; Simon Boecker; Dirk Storm; Tutku Kurt; Özlem Vural; Roderich Süßmuth; Vera Meyer
Journal:  Fungal Biol Biotechnol       Date:  2014-10-14

6.  Diversity and Characterization of Endophytic Fungi Isolated From the Tropical Mangrove Species, Rhizophora mucronata, and Identification of Potential Antagonists Against the Soil-Borne Fungus, Fusarium solani.

Authors:  Tuan Noraida Tuan Hamzah; Shiou Yih Lee; Asep Hidayat; Razak Terhem; Ibrahim Faridah-Hanum; Rozi Mohamed
Journal:  Front Microbiol       Date:  2018-07-25       Impact factor: 5.640

7.  Comparative Structure-Activity Analysis of the Antimicrobial Activity, Cytotoxicity, and Mechanism of Action of the Fungal Cyclohexadepsipeptides Enniatins and Beauvericin.

Authors:  Hamza Olleik; Cendrine Nicoletti; Mickael Lafond; Elise Courvoisier-Dezord; Peiwen Xue; Akram Hijazi; Elias Baydoun; Josette Perrier; Marc Maresca
Journal:  Toxins (Basel)       Date:  2019-09-03       Impact factor: 4.546

Review 8.  Detoxification of Mycotoxins through Biotransformation.

Authors:  Peng Li; Ruixue Su; Ruya Yin; Daowan Lai; Mingan Wang; Yang Liu; Ligang Zhou
Journal:  Toxins (Basel)       Date:  2020-02-14       Impact factor: 4.546

9.  Transport of enniatin B and enniatin B1 across the blood-brain barrier and hints for neurotoxic effects in cerebral cells.

Authors:  Isabel Krug; Matthias Behrens; Melanie Esselen; Hans-Ulrich Humpf
Journal:  PLoS One       Date:  2018-05-16       Impact factor: 3.240

10.  Phylogeny and Mycotoxin Profile of Pathogenic Fusarium Species Isolated from Sudden Decline Syndrome and Leaf Wilt Symptoms on Date Palms (Phoenix dactylifera) in Tunisia.

Authors:  Amal Rabaaoui; Chiara Dall'Asta; Laura Righetti; Antonia Susca; Antonio Francesco Logrieco; Ahmed Namsi; Radhouane Gdoura; Stefaan P O Werbrouck; Antonio Moretti; Mario Masiello
Journal:  Toxins (Basel)       Date:  2021-06-30       Impact factor: 4.546
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.