Literature DB >> 1786037

Effect of a diet rich in linseed oil on complex viscosity and blood pressure in spontaneously hypertensive rats (SHR).

B Dierberger1, M Schäch, I Anadere, M Brändle, R Jacob.   

Abstract

The influence of a diet rich in linseed oil (10% in weight) with a content of 61.2% of alpha-linolenic fatty acid on blood pressure and complex blood viscosity was investigated in spontaneously hypertensive rats. A decrease in blood pressure by 59 mm Hg was found compared to the age-matched, untreated control group. The viscous (eta') and elastic (eta") components of viscosity were also reduced at various shear rates (gamma). The same applies to the aggregation index, which is a measure of the aggregation tendency of red blood cells (RBC). Of course, the effects on blood viscosity cannot explain the observed degree of blood-pressure-lowering. Nevertheless, a decrease in the viscosity can improve the flow conditions in the microcirculation, which may lead to a better oxygen supply.

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Year:  1991        PMID: 1786037     DOI: 10.1007/bf02190706

Source DB:  PubMed          Journal:  Basic Res Cardiol        ISSN: 0300-8428            Impact factor:   17.165


  10 in total

1.  The determination of blood viscoelasticity in clinical hemorheology.

Authors:  H Chmiel; I Anadere; E Walitza
Journal:  Biorheology       Date:  1990       Impact factor: 1.875

2.  A plethysmographic method for measuring systolic blood pressure in the intact rat.

Authors:  F B Byrom; C Wilson
Journal:  J Physiol       Date:  1938-08-15       Impact factor: 5.182

3.  Ultrastructural basis of the mechanism of rouleaux formation.

Authors:  S Chien; K Jan
Journal:  Microvasc Res       Date:  1973-03       Impact factor: 3.514

4.  Viscoelasticity of human blood.

Authors:  G B Thurston
Journal:  Biophys J       Date:  1972-09       Impact factor: 4.033

5.  Shear-dependent interaction of plasma proteins with erythrocytes in blood rheology.

Authors:  S Chien; S Usami; R J Dellenback; M I Gregersen
Journal:  Am J Physiol       Date:  1970-07

6.  Reduction in blood viscosity by eicosapentaenoic acid.

Authors:  S Kobayashi; A Hirai; T Terano; T Hamazaki; Y Tamura; A Kumagai
Journal:  Lancet       Date:  1981-07-25       Impact factor: 79.321

7.  Influence of a diet rich in fish oil on blood pressure, body weight and cardiac hypertrophy in spontaneously hypertensive rats.

Authors:  D von Au; M Brändle; H Rupp; R Jacob
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1988

8.  Long-term effect of mackerel diet on blood pressure, serum lipids and thromboxane formation in patients with mild essential hypertension.

Authors:  P Singer; I Berger; K Lück; C Taube; E Naumann; W Gödicke
Journal:  Atherosclerosis       Date:  1986-12       Impact factor: 5.162

Review 9.  Cardiovascular actions of dietary polyunsaturates and related mechanisms. A state-of-the-art-review.

Authors:  P Hoffmann
Journal:  Prostaglandins Leukot Med       Date:  1986-02

10.  Effect of oral administration of highly purified eicosapentaenoic acid on platelet function, blood viscosity and red cell deformability in healthy human subjects.

Authors:  T Terano; A Hirai; T Hamazaki; S Kobayashi; T Fujita; Y Tamura; A Kumagai
Journal:  Atherosclerosis       Date:  1983-03       Impact factor: 5.162

  10 in total

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