Literature DB >> 1785673

Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19).

U R Kees1, M T Mulcahy, M L Willoughby.   

Abstract

We report here a rare case of intrathoracic undifferentiated carcinoma in an 11-year-old girl. The biopsy tissue stained with antibodies against cytokeratin and carcino-embryonic antigen. The same staining was obtained using a cell line, PER-403, which was derived from the tumor. DNA from PER-403 cells was tested for the presence of Epstein-Barr virus genes, yielding a negative result. The cytogenetic analysis found a translocation t(15;19) (p12;q13), which has not previously been described in a carcinoma.

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Year:  1991        PMID： 1785673     DOI： 10.1097/00043426-199124000-00011

Source DB:  PubMed          Journal:  Am J Pediatr Hematol Oncol        ISSN： 0192-8562


  45 in total

1.  BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19).

Authors:  C A French; I Miyoshi; J C Aster; I Kubonishi; T G Kroll; P Dal Cin; S O Vargas; A R Perez-Atayde; J A Fletcher
Journal:  Am J Pathol       Date:  2001-12       Impact factor: 4.307

2.  NUT midline carcinoma as a primary lung tumor: a case report.

Authors:  Jiashun Cao; Donghong Chen; Fan Yang; Jingjing Yao; Weipeng Zhu; Chuanduo Zhao
Journal:  J Thorac Dis       Date:  2017-12       Impact factor: 2.895

3.  NUT gene rearrangement in a poorly-differentiated carcinoma of the submandibular gland.

Authors:  James Ziai; Chris A French; Eduardo Zambrano
Journal:  Head Neck Pathol       Date:  2010-03-30

4.  Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.

Authors:  Artyom A Alekseyenko; Erica M Walsh; Barry M Zee; Tibor Pakozdi; Peter Hsi; Madeleine E Lemieux; Paola Dal Cin; Tan A Ince; Peter V Kharchenko; Mitzi I Kuroda; Christopher A French
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-08       Impact factor: 11.205

5.  NUT rearrangement is uncommon in human thymic epithelial tumors.

Authors:  Petrini Petrini; Christopher A French; Arun Rajan; Michael J Cameron; Elaine S Jaffe; Paolo A Zucali; Jianwu Xie; Yisong Wang; Giuseppe Giaccone
Journal:  J Thorac Oncol       Date:  2012-04       Impact factor: 15.609

Review 6.  Update on genetically defined lung neoplasms: NUT carcinoma and thoracic SMARCA4-deficient undifferentiated tumors.

Authors:  Kyriakos Chatzopoulos; Jennifer M Boland
Journal:  Virchows Arch       Date:  2021-01-06       Impact factor: 4.064

Review 7.  NUT midline carcinoma of the larynx: an international series and review of the literature.

Authors:  Henrik Hellquist; Christopher A French; Justin A Bishop; Andrés Coca-Pelaz; Evan J Propst; António Paiva Correia; Bo-Yee Ngan; Ronald Grant; Nicole A Cipriani; David Vokes; Rui Henrique; Fernando Pardal; Jose Ramon Vizcaino; Alessandra Rinaldo; Alfio Ferlito
Journal:  Histopathology       Date:  2017-02-21       Impact factor: 5.087

8.  Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro.

Authors:  N Haruki; K S Kawaguchi; S Eichenberger; P P Massion; A Gonzalez; A F Gazdar; J D Minna; D P Carbone; T P Dang
Journal:  J Med Genet       Date:  2005-07       Impact factor: 6.318

9.  "Z4" Complex Member Fusions in NUT Carcinoma: Implications for a Novel Oncogenic Mechanism.

Authors:  Hitoshi Shiota; Janine E Elya; Artyom A Alekseyenko; Pauline M Chou; Shelby A Gorman; Olena Barbash; Kelly Becht; Kristina Danga; Mitzi I Kuroda; Valentina Nardi; Christopher A French
Journal:  Mol Cancer Res       Date:  2018-08-23       Impact factor: 5.852

10.  Differentiation of NUT midline carcinoma by epigenomic reprogramming.

Authors:  Brian E Schwartz; Matthias D Hofer; Madeleine E Lemieux; Daniel E Bauer; Michael J Cameron; Nathan H West; Elin S Agoston; Nicolas Reynoird; Saadi Khochbin; Tan A Ince; Amanda Christie; Katherine A Janeway; Sara O Vargas; Antonio R Perez-Atayde; Jon C Aster; Stephen E Sallan; Andrew L Kung; James E Bradner; Christopher A French
Journal:  Cancer Res       Date:  2011-03-29       Impact factor: 12.701
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