Literature DB >> 17851443

Determination of the three-dimensional structure of Gynoside A in solution using NMR and molecular modeling.

Qian Li1, Zhi-Hong Yao, Yan-Hong Shi, Xin-Sheng Yao, Wen-Cai Ye, Xin Liu.   

Abstract

The three-dimensional structure of Gynoside A, an ocotillone-type triterpenoid glycoside isolated from Gynostemma pentaphyllum, was determined in pyridine-d5 and DMSO-d6 solution through constrained molecular modeling using constraints derived from proton NMR spectra. The calculation yielded well-defined global minima. Except for some quantitative details the overall structure of Gynoside A in pyridine-d5 shared many common features with that in DMSO-d6. The structure in pyridine-d5 had lower energies than that in DMSO-d6 solution.

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Year:  2007        PMID： 17851443      PMCID： PMC6149387          DOI： 10.3390/12040907

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  8 in total

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Review 2.  The bioactivity of saponins: triterpenoid and steroidal glycosides.

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6.  Five new Ocotillone-type saponins from Gynostemma pentaphyllum.

Authors:  Xin Liu; Wencai Ye; Ziyao Mo; Biao Yu; Shouxun Zhao; Houming Wu; Chuntao Che; Renwang Jiang; Thomas C W Mak; W L Wendy Hsiao
Journal:  J Nat Prod       Date:  2004-07       Impact factor: 4.050

7.  Determination of the three-dimensional, solution-phase structure of the macrolide antibiotic oxolide in CD2Cl2 and D2O from NMR constraints.

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Journal:  Magn Reson Chem       Date:  2005-01       Impact factor: 2.447

8.  Structure-activity studies of some oleanane triterpenoid glycosides and their related compounds from the leaves of Tetrapanax papyriferum on anti-inflammatory activities.

Authors:  E Sugishita; S Amagaya; Y Ogihara
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  8 in total

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