Literature DB >> 15270569

Five new Ocotillone-type saponins from Gynostemma pentaphyllum.

Xin Liu1, Wencai Ye, Ziyao Mo, Biao Yu, Shouxun Zhao, Houming Wu, Chuntao Che, Renwang Jiang, Thomas C W Mak, W L Wendy Hsiao.   

Abstract

Five new ocotillone-type saponins, gynosides A-E (1-5), along with 10 known dammarane-type saponins, were isolated from the aerial parts of Gynostemma pentaphyllum. The structures of these new compounds were determined by NMR analysis and acid hydrolysis. The structure and stereochemistry of gynoside A (1) were confirmed by X-ray crystallography.

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Year:  2004        PMID: 15270569     DOI: 10.1021/np034018+

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  A novel antitumor compound nobiliside D isolated from sea cucumber (Holothuria nobilis Selenka).

Authors:  Jia-Jia Zhang; Ke-Qi Zhu
Journal:  Exp Ther Med       Date:  2017-06-23       Impact factor: 2.447

2.  Mechanism of action of gypenosides on type 2 diabetes and non-alcoholic fatty liver disease in rats.

Authors:  Qin He; Jin-Ke Li; Fang Li; Ru-Gui Li; Guo-Qing Zhan; Gang Li; Wei-Xing Du; Hua-Bing Tan
Journal:  World J Gastroenterol       Date:  2015-02-21       Impact factor: 5.742

3.  Determination of the three-dimensional structure of Gynoside A in solution using NMR and molecular modeling.

Authors:  Qian Li; Zhi-Hong Yao; Yan-Hong Shi; Xin-Sheng Yao; Wen-Cai Ye; Xin Liu
Journal:  Molecules       Date:  2007-04-30       Impact factor: 4.411

4.  Tentative identification of 20(S)-protopanaxadiol metabolites in human plasma and urine using ultra-performance liquid chromatography coupled with triple quadrupole time-of-flight mass spectrometry.

Authors:  Jin Ling; Yingjia Yu; Jiakun Long; Yan Li; Jiebing Jiang; Liping Wang; Changjiang Xu; Gengli Duan
Journal:  J Ginseng Res       Date:  2018-04-05       Impact factor: 6.060

5.  Gypenoside XVII, an Active Ingredient from Gynostemma Pentaphyllum, Inhibits C3aR-Associated Synaptic Pruning in Stressed Mice.

Authors:  Man-Man Zhang; Guo-Ming Huo; Jie Cheng; Qiu-Ping Zhang; Na-Zhi Li; Min-Xia Guo; Qing Liu; Guang-Hui Xu; Ji-Xiao Zhu; Cheng-Fu Li; Feng Zhou; Li-Tao Yi
Journal:  Nutrients       Date:  2022-06-10       Impact factor: 6.706

6.  Gynostemma pentaphyllum saponins attenuate inflammation in vitro and in vivo by inhibition of NF-κB and STAT3 signaling.

Authors:  Wing-Yan Wong; Magnolia Muk-Lan Lee; Brandon Dow Chan; Victor Wan-San Ma; Wenchun Zhang; Timothy Tak-Chun Yip; Wing-Tak Wong; William Chi-Shing Tai
Journal:  Oncotarget       Date:  2017-09-18
  6 in total

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