Literature DB >> 17847727

Successful treatment of autophonia with botulinum toxin: case report.

Arno Olthoff1, Rainer Laskawi, Eberhard Kruse.   

Abstract

OBJECTIVES: We sought to treat autophonia due to a patulous eustachian tube using botulinum toxin.
METHODS: Because we assumed that the patulous eustachian tube was caused by abnormal activity of paratubal muscles (tensor and levator veli palatini muscles and salpingopharyngeus muscle), paralysis was performed via injection of botulinum toxin type A in a 45-year-old female professional musician who had had chronic unilateral autophonia for 20 years. In addition to a patient interview, an endoscopic examination of the nasopharynx (posterior rhinoscopy), ear microscopy, and impedance audiometry were performed to verify the diagnosis and the outcome after treatment.
RESULTS: The autophonia disappeared 1 week after treatment. Normalized tympanic ventilation was verified by impedance audiometry after 8 weeks. The period of symptom relief was 9 months.
CONCLUSIONS: The administration of botulinum toxin type A provides a new option in the treatment of patulous eustachian tube. The reliability of this method and the effect of repeated injections remains to be proved in future studies.

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Year:  2007        PMID: 17847727     DOI: 10.1177/000348940711600807

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  6 in total

1.  [The application of botulinum toxin in oromandibular, pharyngeal and laryngeal dystonia].

Authors:  A Olthoff; R Laskawi
Journal:  HNO       Date:  2012-06       Impact factor: 1.284

Review 2.  [Botulinum toxin treatment in the head and neck region: current aspects, developments, and problems].

Authors:  R Laskawi
Journal:  HNO       Date:  2007-06       Impact factor: 1.284

Review 3.  [The patulous eustachian tube-novel surgical approaches].

Authors:  S Schröder; M Lehmann; H Sudhoff; J Ebmeyer
Journal:  HNO       Date:  2013-12       Impact factor: 1.284

Review 4.  [Botulinum toxin in otorhinolaryngology - an update].

Authors:  R Laskawi; A Olthoff
Journal:  HNO       Date:  2017-10       Impact factor: 1.284

Review 5.  The use of botulinum toxin in head and face medicine: an interdisciplinary field.

Authors:  Rainer Laskawi
Journal:  Head Face Med       Date:  2008-03-10       Impact factor: 2.151

6.  Diagnostic approaches to and management options for patulous eustachian tube.

Authors:  Tawfiq Khurayzi; Saad Alenzi; Anwar Alshehri; Abdurrahman Alsanosi
Journal:  Saudi Med J       Date:  2020-06       Impact factor: 1.484

  6 in total

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