Literature DB >> 17846575

Synthesis, characterization and antibacterial activity of azomethine derivatives derived from 2-formylphenoxyacetic acid.

Amjid Iqbal1, Hamid Latif Siddiqui, C M Ashraf, Matloob Ahmad, George W Weaver.   

Abstract

A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR, MS and elemental analysis. The compounds were assayed by the disc diffusion method for antibacterial against Staphylococcus aureus and Escherichia coli. Among the compounds tested, 2a, 2b, 2e, 2g and 2h exhibited good antibacterial activity, almost equal to that of Ciprofloxacin used as standard.

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Year:  2007        PMID： 17846575      PMCID： PMC6149423          DOI： 10.3390/12020245

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  5 in total

1.  Investigation of anticancer activity of macrocyclic Schiff bases by means of 4D-QSAR based on simplex representation of molecular structure.

Authors:  V E Kuz'min; A G Artemenko; R N Lozytska; A S Fedtchouk; V P Lozitsky; E N Muratov; A K Mescheriakov
Journal:  SAR QSAR Environ Res       Date:  2005-06       Impact factor: 3.000

2.  The action of aryloxyaliphatic acids on the permeability of blood vessels.

Authors:  B J NORTHOVER; J VERGHESE
Journal:  J Pharm Pharmacol       Date:  1962-09       Impact factor: 3.765

3.  Pyridoxal phosphate. II. Benzene analogs. 2-Formylphenoxyacetic acids as potential antimetabolites of pyridoxal phosphate.

Authors:  T L Hullar; D L Failla
Journal:  J Med Chem       Date:  1969-05       Impact factor: 7.446

4.  A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones as inhibitors of chorismate synthase.

Authors:  Michael G Thomas; Chris Lawson; Nigel M Allanson; Bruce W Leslie; Joanna R Bottomley; Andrew McBride; Oyinkan A Olusanya
Journal:  Bioorg Med Chem Lett       Date:  2003-02-10       Impact factor: 2.823

5.  Therapeutic potentiation of the immune system by costimulatory Schiff-base-forming drugs.

Authors:  J Rhodes; H Chen; S R Hall; J E Beesley; D C Jenkins; P Collins; B Zheng
Journal:  Nature       Date:  1995-09-07       Impact factor: 49.962
  5 in total
  6 in total

1.  Design, Synthesis, Photophysical Properties, Biological Estimation and Molecular Docking Studies of Novel Schiff Base Derivatives as Potential Urease Inhibitors.

Authors:  Balasaheb D Vanjare; Prasad G Mahajan; Mubashir Hassan; Hussain Raza; Sung-Yum Seo; Seong-Karp Hong; Ki Hwan Lee
Journal:  J Fluoresc       Date:  2018-09-13       Impact factor: 2.217

2.  N'-(2,6-Dichloro-benzyl-idene)-2-hy-droxy-benzohydrazide.

Authors:  Yawar Baig; Hamid Latif Siddiqui; Waseeq Ahmad Siddiqui; Ghulam Mustafa; Harald Krautscheid
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-25

3.  Novel glitazones as PPARγ agonists: molecular design, synthesis, glucose uptake activity and 3D QSAR studies.

Authors:  Subhankar P Mandal; Aakriti Garg; P Prabitha; Ashish D Wadhwani; Laxmi Adhikary; B R Prashantha Kumar
Journal:  Chem Cent J       Date:  2018-12-19       Impact factor: 4.215

4.  Synthesis, biological evaluation of antioxidant-antibacterial activities and computational studies of novel anthracene- and pyrene-based Schiff base derivatives.

Authors:  Ayşegül GÜmÜŞ; Veysi OkumuŞ; Selçuk GÜmÜŞ
Journal:  Turk J Chem       Date:  2020-08-18       Impact factor: 1.239

5.  1-(4-Bromo-phen-yl)-2-(2-chloro-phen-oxy)ethanone.

Authors:  Seema S Shenvi; Arun M Isloor; Thomas Gerber; Eric Hosten; Richard Betz
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-11-30

6.  Synthesis and antibacterial activity of Schiff bases and amines derived from alkyl 2-(2-formyl-4-nitrophenoxy)alkanoates.

Authors:  Agata Goszczyńska; Halina Kwiecień; Karol Fijałkowski
Journal:  Med Chem Res       Date:  2015-07-15       Impact factor: 1.965
  6 in total

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