Literature DB >> 12565943

A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones as inhibitors of chorismate synthase.

Michael G Thomas1, Chris Lawson, Nigel M Allanson, Bruce W Leslie, Joanna R Bottomley, Andrew McBride, Oyinkan A Olusanya.   

Abstract

A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones was identified as potent inhibitors of bacterial chorismate synthase. The 2'-hydroxy-4'-pentoxy analogue 33 is a potent inhibitor of Streptococcus pneumoniae chorismate synthase.

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Year:  2003        PMID： 12565943     DOI： 10.1016/s0960-894x(02)00957-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  Oxidative stress in liver cell culture from mullet, Liza klunzingeri, induced by short-term exposure to benzo[a]pyrene and nonylphenol.

Authors:  Negin Salamat; Negin Derakhshesh
Journal:  Fish Physiol Biochem       Date:  2020-03-12       Impact factor: 2.794

2.  Biophysical and In-Silico Studies of Phytochemicals Targeting Chorismate Synthase from Drug-Resistant Moraxella Catarrhalis.

Authors:  Neetu Neetu; Monica Sharma; Jai Krishna Mahto; Pravindra Kumar
Journal:  Protein J       Date:  2020-10-10       Impact factor: 2.371

3.  Regioselective alkylation of 2,4-dihydroxybenzyaldehydes and 2,4-dihydroxyacetophenones.

Authors:  Aziza Frank; Negar Hamidi; Fengtian Xue
Journal:  Tetrahedron Lett       Date:  2022-03-23       Impact factor: 2.032

4.  An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway.

Authors:  Rok Frlan
Journal:  Antibiotics (Basel)       Date:  2022-05-17

5.  Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.

Authors:  Sidhartha Chaudhury; Mohamed Diwan M Abdulhameed; Narender Singh; Gregory J Tawa; Patrik M D'haeseleer; Adam T Zemla; Ali Navid; Carol E Zhou; Matthew C Franklin; Jonah Cheung; Michael J Rudolph; James Love; John F Graf; David A Rozak; Jennifer L Dankmeyer; Kei Amemiya; Simon Daefler; Anders Wallqvist
Journal:  PLoS One       Date:  2013-05-21       Impact factor: 3.240

6.  Synthesis, characterization and antibacterial activity of azomethine derivatives derived from 2-formylphenoxyacetic acid.

Authors:  Amjid Iqbal; Hamid Latif Siddiqui; C M Ashraf; Matloob Ahmad; George W Weaver
Journal:  Molecules       Date:  2007-02-22       Impact factor: 4.411

Review 7.  Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs.

Authors:  José E S Nunes; Mario A Duque; Talita F de Freitas; Luiza Galina; Luis F S M Timmers; Cristiano V Bizarro; Pablo Machado; Luiz A Basso; Rodrigo G Ducati
Journal:  Molecules       Date:  2020-03-11       Impact factor: 4.411
  7 in total

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