BACKGROUND: Many studies have demonstrated a positive association between air pollutants and emergency visits for asthma. However, few studies have included pollen when analysing this relationship in mild-moderate asthmatic patients. OBJECTIVE: To determine the importance of the pollutants such as ozone (O(3)), particles (PM(10)), nitrogen dioxide (NO(2)) and sulphur dioxide (SO(2)) in the clinical course of mild-moderate pollen-allergic asthmatic patients from two Spanish towns in La Mancha: Puertollano (high pollution levels) and Ciudad Real (low pollution levels). METHODS: We used a Poisson regression model to study a cohort of 137 patients from Puertollano and Ciudad Real during two pollen seasons (2000-2001) and analysed the relationship between air pollutant and pollen levels and daily symptoms, the medication used and peak-flow measurements. RESULTS: The number of asthma symptoms and the mean values of the PM(10), SO(2) and NO(2) levels were higher in Puertollano than in Ciudad Real. In Puertollano, the risk of asthma increased by 6% with a 3-day lag for PM(10), by 8% with a 3-day lag for O(3), by 4% with a 1-day lag for SO(2) and by 15% with a 3-day lag for O(3) when its values exceeded the health threshold (P < 0.05). CONCLUSIONS: The air pollution levels in Puertollano were associated with an increased risk of asthma symptoms in pollen-allergic asthmatic patients com pared with a similar group from Ciudad Real.
BACKGROUND: Many studies have demonstrated a positive association between air pollutants and emergency visits for asthma. However, few studies have included pollen when analysing this relationship in mild-moderate asthmatic patients. OBJECTIVE: To determine the importance of the pollutants such as ozone (O(3)), particles (PM(10)), nitrogen dioxide (NO(2)) and sulphur dioxide (SO(2)) in the clinical course of mild-moderate pollen-allergic asthmaticpatients from two Spanish towns in La Mancha: Puertollano (high pollution levels) and Ciudad Real (low pollution levels). METHODS: We used a Poisson regression model to study a cohort of 137 patients from Puertollano and Ciudad Real during two pollen seasons (2000-2001) and analysed the relationship between air pollutant and pollen levels and daily symptoms, the medication used and peak-flow measurements. RESULTS: The number of asthma symptoms and the mean values of the PM(10), SO(2) and NO(2) levels were higher in Puertollano than in Ciudad Real. In Puertollano, the risk of asthma increased by 6% with a 3-day lag for PM(10), by 8% with a 3-day lag for O(3), by 4% with a 1-day lag for SO(2) and by 15% with a 3-day lag for O(3) when its values exceeded the health threshold (P < 0.05). CONCLUSIONS: The air pollution levels in Puertollano were associated with an increased risk of asthma symptoms in pollen-allergic asthmaticpatients com pared with a similar group from Ciudad Real.
Authors: Richard Toro A; Alicia Córdova J; Mauricio Canales; Raul G E Morales S; Pedro Mardones P; Manuel A Leiva G Journal: PLoS One Date: 2015-05-06 Impact factor: 3.240
Authors: Jean Bousquet; Josep M Anto; Isabella Annesi-Maesano; Toni Dedeu; Eve Dupas; Jean-Louis Pépin; Landry Stephane Zeng Eyindanga; Sylvie Arnavielhe; Julia Ayache; Xavier Basagana; Samuel Benveniste; Nuria Calves Venturos; Hing Kin Chan; Mehdi Cheraitia; Yves Dauvilliers; Judith Garcia-Aymerich; Ingrid Jullian-Desayes; Chitra Dinesh; Daniel Laune; Jade Lu Dac; Ismael Nujurally; Giovanni Pau; Robert Picard; Xavier Rodo; Renaud Tamisier; Michael Bewick; Nils E Billo; Wienczyslawa Czarlewski; Joao Fonseca; Ludger Klimek; Oliver Pfaar; Jean-Marc Bourez Journal: Clin Transl Allergy Date: 2018-09-17 Impact factor: 5.871