Literature DB >> 1784147

In vivo-in vitro correlation of salbutamol release from a controlled release osmotic pump delivery system.

C Civiale1, W A Ritschel, G K Shiu, J M Aiache, E Beyssac.   

Abstract

The drug release of salbutamol from a controlled release (osmotic pump) tablet was determined in vitro by four different dissolution apparatuses. From published in vivo data, percent of drug absorbed and percent of drug released in vivo were estimated. The highest correlation was obtained between percentage released in vitro versus percentage released in vivo using polynomial regression.

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Year:  1991        PMID: 1784147

Source DB:  PubMed          Journal:  Methods Find Exp Clin Pharmacol        ISSN: 0379-0355


  3 in total

1.  Evaluation of USP apparatus 3 for dissolution testing of immediate-release products.

Authors:  Lawrence X Yu; Jin T Wang; Ajaz S Hussain
Journal:  AAPS PharmSci       Date:  2002

Review 2.  In vitro/in vivo correlations: scientific implications and standardisation.

Authors:  J M Cardot; E Beyssac
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1993 Jan-Mar       Impact factor: 2.441

3.  Influence of route of administration and dosage form in the pharmacokinetics and bioavailability of salbutamol.

Authors:  R M Hernández; A R Gascón; M B Calvo; C Caramella; U Conte; A Domínguez-Gil; J L Pedraz
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1997 Apr-Jun       Impact factor: 2.569

  3 in total

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