Literature DB >> 1784044

Effect of arginine on immune function in rats with obstructive jaundice.

H Li1, S T Xiong, S X Zhang, Y Luo, Z H Feng.   

Abstract

In this study we used an experimental model produced by bile duct ligation (BDL) in rats to demonstrate relation between immune function and susceptibility to infection associated with obstructive jaundice and immunoregulatory effect of arginine in BDL rats. Our experimental results showed that thymus weight, content of lymphocytes in thymus and responsiveness to Con A in vitro were dramatically reduced in BDL rats as compared to rats with sham operation and that the impairment of lymphocyte function was significantly related to the susceptibility to infection. Arginine, as a T cell stimulator, markedly improved immune function and decreased susceptibility to infection of BDL rats.

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Year:  1991        PMID： 1784044     DOI： 10.1007/bf02888126

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN： 0257-716X


  7 in total

1.  A soluble suppressor T cell factor protects against experimental intraabdominal abscesses.

Authors:  D F Zaleznik; R W Finberg; M E Shapiro; A B Onderdonk; D L Kasper
Journal:  J Clin Invest       Date:  1985-03       Impact factor: 14.808

Review 2.  Sepsis and septic shock--a review of laboratory models and a proposal.

Authors:  K A Wichterman; A E Baue; I H Chaudry
Journal:  J Surg Res       Date:  1980-08       Impact factor: 2.192

3.  Immune status in mice with experimental biliary obstruction.

Authors:  M Pinto; A Kaplun
Journal:  Clin Immunol Immunopathol       Date:  1980-08

4.  Impaired specific cell-mediated immunity in experimental biliary obstruction and its reversibility by internal biliary drainage.

Authors:  P T Roughneen; D J Gouma; A D Kulkarni; W F Fanslow; B J Rowlands
Journal:  J Surg Res       Date:  1986-08       Impact factor: 2.192

5.  Intravenous hyperalimentation with high arginine levels improves wound healing and immune function.

Authors:  A Barbul; R S Fishel; S Shimazu; H L Wasserkrug; N N Yoshimura; R C Tao; G Efron
Journal:  J Surg Res       Date:  1985-04       Impact factor: 2.192

6.  Stimulation of T cell immunity by arginine enhances survival in peritonitis.

Authors:  H P Madden; R J Breslin; H L Wasserkrug; G Efron; A Barbul
Journal:  J Surg Res       Date:  1988-06       Impact factor: 2.192

7.  Arginine stimulates lymphocyte immune response in healthy human beings.

Authors:  A Barbul; D A Sisto; H L Wasserkrug; G Efron
Journal:  Surgery       Date:  1981-08       Impact factor: 3.982
  7 in total

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