Literature DB >> 17822826

Targeting telomeres and telomerase.

Anne De Cian1, Laurent Lacroix, Céline Douarre, Nassima Temime-Smaali, Chantal Trentesaux, Jean-François Riou, Jean-Louis Mergny.   

Abstract

Telomeres and telomerase represent, at least in theory, an extremely attractive target for cancer therapy. The objective of this review is to present the latest view on the mechanism(s) of action of telomerase inhibitors, with an emphasis on a specific class of telomere ligands called G-quadruplex ligands, and to discuss their potential use in oncology.

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Year:  2007        PMID： 17822826     DOI： 10.1016/j.biochi.2007.07.011

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  104 in total

1.  Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design.

Authors:  Jixun Dai; Megan Carver; Laurence H Hurley; Danzhou Yang
Journal:  J Am Chem Soc       Date:  2011-10-14       Impact factor: 15.419

Review 2.  Telomere biology: Rationale for diagnostics and therapeutics in cancer.

Authors:  Philippe Rousseau; Chantal Autexier
Journal:  RNA Biol       Date:  2015-08-20       Impact factor: 4.652

3.  Biological activity of enantiomeric complexes [PtCl(2)L (2)] (L (2) is aromatic bisphosphanes and aromatic diamines).

Authors:  Sophie Bombard; Marzia Bruna Gariboldi; Elena Monti; Elisabetta Gabano; Luca Gaviglio; Mauro Ravera; Domenico Osella
Journal:  J Biol Inorg Chem       Date:  2010-03-24       Impact factor: 3.358

Review 4.  In vivo veritas: using yeast to probe the biological functions of G-quadruplexes.

Authors:  Jay E Johnson; Jasmine S Smith; Marina L Kozak; F Brad Johnson
Journal:  Biochimie       Date:  2008-02-21       Impact factor: 4.079

5.  Molecular dynamics and principal components analysis of human telomeric quadruplex multimers.

Authors:  Shozeb Haider; Gary N Parkinson; Stephen Neidle
Journal:  Biophys J       Date:  2008-03-28       Impact factor: 4.033

6.  Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity.

Authors:  Mariusz P Gajewski; Howard Beall; Mark Schnieder; Sarah M Stranahan; Michael D Mosher; Kevin C Rider; Nicholas R Natale
Journal:  Bioorg Med Chem Lett       Date:  2009-06-13       Impact factor: 2.823

7.  The relationship between telomere length and clinicopathologic characteristics in colorectal cancers among Tunisian patients.

Authors:  Raja Mzahma; Maher Kharrat; Fadhel Fetiriche; Mounir Ben Moussa; Zoubeir Ben Safta; Chadli Dziri; AbdelJelil Zaouche; Habiba Chaabouni-Bouhamed
Journal:  Tumour Biol       Date:  2015-06-06

8.  Down regulation of human telomerase reverse transcriptase (hTERT) expression by BIBR1532 in human glioblastoma LN18 cells.

Authors:  C Lavanya; Manjunatha M Venkataswamy; M K Sibin; M M Srinivas Bharath; G K Chetan
Journal:  Cytotechnology       Date:  2018-03-15       Impact factor: 2.058

Review 9.  Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability.

Authors:  Jonathan B Chaires
Journal:  FEBS J       Date:  2009-11-27       Impact factor: 5.542

10.  G-quadruplex nucleic acids as therapeutic targets.

Authors:  Shankar Balasubramanian; Stephen Neidle
Journal:  Curr Opin Chem Biol       Date:  2009-06-08       Impact factor: 8.822
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