OBJECTIVE: To examine relationships between speed of eating and insulin resistance. METHODS: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m(2)) and 761 female (46.3 y and 21.8 kg/m(2)) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). RESULTS: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p<0.001, for trend) and in women (p<0.01). Adjusting for BMI, this positive relationship appeared only in men (p=0.03). CONCLUSIONS: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.
OBJECTIVE: To examine relationships between speed of eating and insulin resistance. METHODS: Cross-sectional study of 2704 male (mean age and BMI: 48.2 y and 23.3 kg/m(2)) and 761 female (46.3 y and 21.8 kg/m(2)) non-diabetic Japanese civil servants, 75% clerical, and 25% manual laborers, using a two-part questionnaire on life-style factors and diet history with self-assessment of categorical speed of eating and energy intake over a 1-month period. We measured BMI, blood glucose and insulin concentrations and calculated insulin resistance using the homeostasis model assessment of insulin resistance: (HOMA-IR). RESULTS: BMI correlated with eating rate in both sexes, and with daily energy intake in men. Multiple regression analysis of log HOMA-IR by categorical speed of eating, adjusting for age, energy intake and lifestyle factors showed a statistically significant gradual increase in HOMA-IR with increases in relative eating rate in men (p<0.001, for trend) and in women (p<0.01). Adjusting for BMI, this positive relationship appeared only in men (p=0.03). CONCLUSIONS: Our results suggest that eating fast is independently associated with insulin resistance in middle-aged Japanese men and women.
Authors: T Ohkuma; H Fujii; M Iwase; Y Kikuchi; S Ogata; Y Idewaki; H Ide; Y Doi; Y Hirakawa; N Mukai; T Ninomiya; K Uchida; U Nakamura; S Sasaki; Y Kiyohara; T Kitazono Journal: Diabetologia Date: 2012-10-13 Impact factor: 10.122
Authors: Mark L Wahlqvist; Stephen A Krawetz; Nico S Rizzo; Maria Gloria Dominguez-Bello; Linda M Szymanski; Shari Barkin; Ann Yatkine; Robert A Waterland; Julie A Mennella; Mina Desai; Michael G Ross; Nancy F Krebs; Bridget E Young; Jane Wardle; Christiane D Wrann; John G Kral Journal: Ann N Y Acad Sci Date: 2015-06-02 Impact factor: 5.691