Literature DB >> 17816019

Total synthesis of the L-hexoses.

S Y Ko, A W Lee, S Masamune, L A Reed, K B Sharpless, F J Walker.   

Abstract

Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four steps. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses.

Entities:  

Year:  1983        PMID: 17816019     DOI: 10.1126/science.220.4600.949

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  26 in total

Review 1.  Asymmetric catalysis in complex target synthesis.

Authors:  Mark S Taylor; Eric N Jacobsen
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-12       Impact factor: 11.205

2.  Structure activity relationship study of Mezzettiasides natural products and their four new disaccharide analogues for anticancer/antibacterial activity.

Authors:  Penny J Beuning; George A O'Doherty; Sumit O Bajaj; Pei Shi
Journal:  Medchemcomm       Date:  2014-08       Impact factor: 3.597

3.  De novo asymmetric synthesis of the mezzettiaside family of natural products via the iterative use of a dual B-/Pd-catalyzed glycosylation.

Authors:  Sumit O Bajaj; Ehesan U Sharif; Novruz G Akhmedov; George A O'Doherty
Journal:  Chem Sci       Date:  2014-06       Impact factor: 9.825

4.  Polyol synthesis through hydrocarbon oxidation: de novo synthesis of L-galactose.

Authors:  Dustin J Covell; Nicolaas A Vermeulen; Nathan A Labenz; M Christina White
Journal:  Angew Chem Int Ed Engl       Date:  2006-12-11       Impact factor: 15.336

5.  De novo asymmetric syntheses of D- and L-talose via an iterative dihydroxylation of dienoates.

Authors:  Md Moinuddin Ahmed; George A O'Doherty
Journal:  J Org Chem       Date:  2005-12-09       Impact factor: 4.354

6.  Merremoside D: de novo synthesis of the purported structure, NMR analysis, and comparison of spectral data.

Authors:  Ehesan U Sharif; Hua-Yu Leo Wang; Novruz G Akhmedov; George A O'Doherty
Journal:  Org Lett       Date:  2013-12-19       Impact factor: 6.005

7.  Achmatowicz Reaction and its Application in the Syntheses of Bioactive Molecules.

Authors:  Arun K Ghosh; Margherita Brindisi
Journal:  RSC Adv       Date:  2016-11-24       Impact factor: 3.361

8.  Synthesis of orthogonally protected bacterial, rare-sugar and D-glycosamine building blocks.

Authors:  Madhu Emmadi; Suvarn S Kulkarni
Journal:  Nat Protoc       Date:  2013-09-05       Impact factor: 13.491

9.  Iridium-catalyzed allylation of chiral β-stereogenic alcohols: bypassing discrete formation of epimerizable aldehydes.

Authors:  Daniel C Schmitt; Anne-Marie R Dechert-Schmitt; Michael J Krische
Journal:  Org Lett       Date:  2012-12-11       Impact factor: 6.005

10.  Palladium-catalyzed decarboxylative allylic alkylation of diastereomeric β-ketoesters.

Authors:  Sandy Ma; Corey M Reeves; Robert A Craig; Brian M Stoltz
Journal:  Tetrahedron       Date:  2014-07-08       Impact factor: 2.457

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