E Ainy1, P Mirmiran, S Zahedi Asl, F Azizi. 1. Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. s.samavatian@gmail.com
Abstract
OBJECTIVE: This study was conducted to assess the prevalence of metabolic syndrome (MetS) in Tehranian women during menopausal transition. DESIGN: In this cross sectional study 2182 subjects, pre-menopausal (pre-M) n=537, menopausal (M) n=311 and post-menopausal (post-M) n=1334 were selected from 15005 participants of the TLGS and assessed for MetS risk factors. All MetS components were evaluated following age adjustment according to the ATPIII criteria. RESULTS: The mean ages of post-M, M and pre-M women were 61.0+/-4.3, 53.0+/-4.0 and 47.0+/-1.9 years, respectively. The prevalence of MetS in subjects was 63% (53%, 54% and 69%) in pre-M, M and post-M women respectively. HDL-c levels was significantly higher in post-M women in comparison to pre-M women (p<0.001). TG levels, FPG and waist circumference was significantly higher in post-M women in comparison to pre-M women (p<0.05). The most frequent markers of MetS were low HDL-c and high diastolic blood pressure in post-M women. CONCLUSION: It is concluded that the frequency of MetS is significantly higher in post-M women as compared to pre-M women; low HDL-c and high diastolic blood pressure is the most frequent feature in comparison to other factors.
OBJECTIVE: This study was conducted to assess the prevalence of metabolic syndrome (MetS) in Tehranian women during menopausal transition. DESIGN: In this cross sectional study 2182 subjects, pre-menopausal (pre-M) n=537, menopausal (M) n=311 and post-menopausal (post-M) n=1334 were selected from 15005 participants of the TLGS and assessed for MetS risk factors. All MetS components were evaluated following age adjustment according to the ATPIII criteria. RESULTS: The mean ages of post-M, M and pre-M women were 61.0+/-4.3, 53.0+/-4.0 and 47.0+/-1.9 years, respectively. The prevalence of MetS in subjects was 63% (53%, 54% and 69%) in pre-M, M and post-M women respectively. HDL-c levels was significantly higher in post-M women in comparison to pre-M women (p<0.001). TG levels, FPG and waist circumference was significantly higher in post-M women in comparison to pre-M women (p<0.05). The most frequent markers of MetS were low HDL-c and high diastolic blood pressure in post-M women. CONCLUSION: It is concluded that the frequency of MetS is significantly higher in post-M women as compared to pre-M women; low HDL-c and high diastolic blood pressure is the most frequent feature in comparison to other factors.
Authors: Samir Ben Ali; Hanen Belfki-Benali; Hajer Aounallah-Skhiri; Pierre Traissac; Bernard Maire; Francis Delpeuch; Noureddine Achour; Habiba Ben Romdhane Journal: Biomed Res Int Date: 2014-03-31 Impact factor: 3.411