Literature DB >> 17767156

Variation in complement factor 3 is associated with risk of age-related macular degeneration.

Julian B Maller1, Jesen A Fagerness, Robyn C Reynolds, Benjamin M Neale, Mark J Daly, Johanna M Seddon.   

Abstract

The association of variants in complement factors H and B with age-related macular degeneration has led to more intense genetic and functional analysis of the complement pathway. We identify a nonsynonymous coding change in complement factor 3 that is strongly associated with risk of age-related macular degeneration in a large case-control sample.

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Year:  2007        PMID： 17767156     DOI： 10.1038/ng2131

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  209 in total

1.  Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models.

Authors:  Yi Yu; Robyn Reynolds; Bernard Rosner; Mark J Daly; Johanna M Seddon
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-03-21       Impact factor: 4.799

Review 2.  How does the macula protect itself from oxidative stress?

Authors:  James T Handa
Journal:  Mol Aspects Med       Date:  2012-04-05

Review 3.  Animal models of age related macular degeneration.

Authors:  Mark E Pennesi; Martha Neuringer; Robert J Courtney
Journal:  Mol Aspects Med       Date:  2012-06-15

4.  Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Authors:  Wei Chen; Dwight Stambolian; Albert O Edwards; Kari E Branham; Mohammad Othman; Johanna Jakobsdottir; Nirubol Tosakulwong; Margaret A Pericak-Vance; Peter A Campochiaro; Michael L Klein; Perciliz L Tan; Yvette P Conley; Atsuhiro Kanda; Laura Kopplin; Yanming Li; Katherine J Augustaitis; Athanasios J Karoukis; William K Scott; Anita Agarwal; Jaclyn L Kovach; Stephen G Schwartz; Eric A Postel; Matthew Brooks; Keith H Baratz; William L Brown; Alexander J Brucker; Anton Orlin; Gary Brown; Allen Ho; Carl Regillo; Larry Donoso; Lifeng Tian; Brian Kaderli; Dexter Hadley; Stephanie A Hagstrom; Neal S Peachey; Ronald Klein; Barbara E K Klein; Norimoto Gotoh; Kenji Yamashiro; Frederick Ferris Iii; Jesen A Fagerness; Robyn Reynolds; Lindsay A Farrer; Ivana K Kim; Joan W Miller; Marta Cortón; Angel Carracedo; Manuel Sanchez-Salorio; Elizabeth W Pugh; Kimberly F Doheny; Maria Brion; Margaret M Deangelis; Daniel E Weeks; Donald J Zack; Emily Y Chew; John R Heckenlively; Nagahisa Yoshimura; Sudha K Iyengar; Peter J Francis; Nicholas Katsanis; Johanna M Seddon; Jonathan L Haines; Michael B Gorin; Gonçalo R Abecasis; Anand Swaroop
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-12       Impact factor: 11.205

Review 5.  Age-related macular degeneration: genetic and environmental factors of disease.

Authors:  Yuhong Chen; Matthew Bedell; Kang Zhang
Journal:  Mol Interv       Date:  2010-10

6.  Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration susceptibility.

Authors:  Kylee L Spencer; Lana M Olson; Nathalie Schnetz-Boutaud; Paul Gallins; Gaofeng Wang; William K Scott; Anita Agarwal; Johanna Jakobsdottir; Yvette Conley; Daniel E Weeks; Michael B Gorin; Margaret A Pericak-Vance; Jonathan L Haines
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-03-28       Impact factor: 4.799

7.  Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Authors:  Johanna M Seddon; Robyn Reynolds; Yi Yu; Mark J Daly; Bernard Rosner
Journal:  Ophthalmology       Date:  2011-09-29       Impact factor: 12.079

Review 8.  Retinal remodeling.

Authors:  B W Jones; M Kondo; H Terasaki; Y Lin; M McCall; R E Marc
Journal:  Jpn J Ophthalmol       Date:  2012-05-30       Impact factor: 2.447

9.  Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways.

Authors:  Mark W Logue; Matthew Schu; Badri N Vardarajan; John Farrell; Kathryn L Lunetta; Gyungah Jun; Clinton T Baldwin; Margaret M Deangelis; Lindsay A Farrer
Journal:  Neurobiol Aging       Date:  2013-12-19       Impact factor: 4.673

10.  Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.

Authors:  Roxana A Radu; Jane Hu; Zhichun Jiang; Dean Bok
Journal:  J Biol Chem       Date:  2014-02-18       Impact factor: 5.157
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