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Literature DB >> 17760644

Reversible optic neuropathy due to metronidazole.

Nicole M McGrath, Brian Kent-Smith, Dianne M Sharp.

Abstract

Metronidazole is a little known cause of drug-induced optic neuropathy. We report a patient who developed progressive visual loss after an 8-month course of Metronidazole. Electrophysiology confirmed a bilateral optic neuropathy. Her vision improved dramatically with cessation of the drug.

Entities: Chemical Disease Species

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Year: 2007 PMID： 17760644 DOI： 10.1111/j.1442-9071.2007.01537.x

Source DB: PubMed Journal: Clin Exp Ophthalmol ISSN： 1442-6404 Impact factor: 4.207

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Cited

14 in total

1. Cases: Reversible cerebellar syndrome caused by metronidazole.

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2. Metronidazole-induced central and peripheral nervous system toxicity.

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Review 5. Neurotoxic effects associated with antibiotic use: management considerations.

Authors: Marie F Grill; Rama K Maganti
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6. Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis.

Authors: Matthew W Carroll; Doosoo Jeon; James M Mountz; Jong Doo Lee; Yeon Joo Jeong; Nadeem Zia; Myungsun Lee; Jongseok Lee; Laura E Via; Soyoung Lee; Seok-Yong Eum; Sung-Joong Lee; Lisa C Goldfeder; Ying Cai; Boyoung Jin; Youngran Kim; Taegwon Oh; Ray Y Chen; Lori E Dodd; Wenjuan Gu; Veronique Dartois; Seung-Kyu Park; Cheon Tae Kim; Clifton E Barry; Sang-Nae Cho
Journal: Antimicrob Agents Chemother Date: 2013-06-03 Impact factor: 5.191

Reversible optic neuropathy due to metronidazole.

1. Cases: Reversible cerebellar syndrome caused by metronidazole.

2. Metronidazole-induced central and peripheral nervous system toxicity.

3. Antibiotic-induced neurotoxicity.

4. Neurological and Psychiatric Adverse Effects of Antimicrobials.

Review 5. Neurotoxic effects associated with antibiotic use: management considerations.

6. Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis.

7. Clinical efficacy of 12-h metronidazole dosing regimens in patients with anaerobic or mixed anaerobic infections.

8. Metronidazole-Induced Irreversible Optic Neuropathy.

9. Metronidazole induced cerebellar ataxia.

10. Metronidazole-induced encephalopathy in a patient with infectious colitis: a case report.