Literature DB >> 1774184

The porcine PGD gene is preferentially lost from chromosome 6 in pig x rodent somatic cell hybrids.

P D Thomsen1, A A Bosma, U Kaufmann, I Harbitz.   

Abstract

The 6-phosphogluconate dehydrogenase (PGD) and glucose phosphate isomerase (GPI) genes are both located on chromosome 6 in the pig (Sus scrofa domestica). Nonetheless, the PGD gene was absent in a total of 17 GPI-positive cell lines found in three independently derived panels of pig x rodent somatic cell hybrids. In most of these cell lines we found an apparently normal pig chromosome 6 at cytogenetic analysis. These results suggest instability of the porcine PGD gene region in interspecies hybrid cells.

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Year:  1991        PMID: 1774184     DOI: 10.1111/j.1601-5223.1991.tb00347.x

Source DB:  PubMed          Journal:  Hereditas        ISSN: 0018-0661            Impact factor:   3.271


  2 in total

1.  Characterization of pig-mink cell hybrids: assignment of the TK1 and UMPH2 genes to pig chromosome 12.

Authors:  N S Zhdanova; N M Astakhova; S B Kuznetsov; L Schuler; O L Serov
Journal:  Mamm Genome       Date:  1994-12       Impact factor: 2.957

2.  Isolation of region-specific probes from pig chromosome 6 by coincidence cloning.

Authors:  E Frengen; P D Thomsen; A Schmitz; G Frelat; W Davies
Journal:  Mamm Genome       Date:  1994-08       Impact factor: 2.957

  2 in total

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