Literature DB >> 17721296

Intacs for keratoconus and post-LASIK ectasia: mechanical versus femtosecond laser-assisted channel creation.

Karen G Carrasquillo1, Janet Rand, Jonathan H Talamo.   

Abstract

PURPOSE: To evaluate the efficacy of intracorneal ring segments to treat keratoconus and post-laser in situ keratomileusis (LASIK) keratectasia implanted by using either mechanical dissection or a femtosecond laser.
METHODS: Thirty-three eyes of 29 patients had intracorneal ring segments implanted by using mechanical dissection (17 eyes) or a femtosecond laser (16 eyes). Mean follow-up was 10.3 months. Parameters assessed before and after surgery included uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refractive spherical equivalent (MRSE), refractive cylinder (RC), best contact lens-corrected visual acuity (BCLVA), and contact lens tolerance.
RESULTS: Statistically significant changes occurred for all parameters when we analyzed all 33 eyes as 1 group. Mean UCVA LogMar values improved from 1.0 +/- 0.3 (20/200) to 0.6 +/- 0.4 (20/80) (P < 0.0005). Mean BSCVA changed from 0.3 +/- 0.2 (20/40) to 0.2 +/- 0.2 (20/30) (10%; P < 0.05), and MRSE from -9 +/- 4 to -7 +/- 4 D (P < 0.05; 20%). There was a decrease of 0.5 D or more of RC in 62% of eyes. BCLVA improved from 0.2 +/- 0.2 (20/30) to 0.1 +/- 0.1 (20/25) after surgery (P < 0.02). Contact lens tolerance improved in 81% of eyes. There was no statistically significant difference in outcomes between mechanical dissection and femtosecond laser-assisted techniques. However, although statistical power was adequate to detect changes in clinical parameters as a result of surgery, it was not sufficient to conclusively show such differences between surgical techniques.
CONCLUSIONS: For mild to moderate cases of keratoconus and post-LASIK keratectasia, the use of a femtosecond laser for Intacs channel creation seems as effective as mechanical dissection. Future studies are warranted to further evaluate channel creation by a femtosecond laser.

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Year:  2007        PMID: 17721296     DOI: 10.1097/ICO.0b013e31811dfa66

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  30 in total

1.  Visual outcomes after femtosecond-assisted intracorneal MyoRing implantation: 18 months of follow-up.

Authors:  Masoomeh Mohebbi; Hassan Hashemi; Soheila Asgari; Sara Bigdeli; Kambiz Ameli Zamani
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-12-29       Impact factor: 3.117

Review 2.  INTACS for keratoconus.

Authors:  Yaron S Rabinowitz
Journal:  Int Ophthalmol Clin       Date:  2006

3.  [Avoidance and management of complications in laser in situ keratomileusis].

Authors:  T Kohnen; O K Klaproth
Journal:  Ophthalmologe       Date:  2013-07       Impact factor: 1.059

4.  Outcome of complete intrastromal ring implantation using femtosecond laser in pellucid marginal degeneration.

Authors:  M Jabbarvand; H Hashemian; M Khodaparast; F Bazvand; A Beheshtnejad
Journal:  Eye (Lond)       Date:  2015-03-27       Impact factor: 3.775

5.  Post-LASIK ectasia treated with intrastromal corneal ring segments and corneal crosslinking.

Authors:  Kay Lam; Dan B Rootman; Alejandro Lichtinger; David S Rootman
Journal:  Digit J Ophthalmol       Date:  2013-01-06

6.  Intrastromal corneal ring segments for treating keratoconus.

Authors:  Karla Zadnik; Sarah Money; Kristina Lindsley
Journal:  Cochrane Database Syst Rev       Date:  2019-05-14

Review 7.  INTACS for keratoconus and ectasia after LASIK.

Authors:  Yaron S Rabinowitz
Journal:  Int Ophthalmol Clin       Date:  2013

8.  Treatment of keratoectasia after LASIK by intrastromal corneal ring segments in two patients who had no preoperative risk factors.

Authors:  Minoru Tomita; Naoko Inoue; Tadahiko Tsuru
Journal:  Clin Ophthalmol       Date:  2010-07-30

9.  Intrastromal corneal ring implants for corneal thinning disorders: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2009-04-01

Review 10.  Pediatric keratoconus: a review of the literature.

Authors:  Sabrina Mukhtar; Balamurali K Ambati
Journal:  Int Ophthalmol       Date:  2017-08-29       Impact factor: 2.031

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