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Literature DB >> 17710096

Targeting the spliceosome.

Brian Rymond.

Abstract

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Substances：

Year: 2007 PMID： 17710096 DOI： 10.1038/nchembio0907-533

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

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13 in total

1. Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.

Authors: Chandraiah Lagisetti; Alan Pourpak; Tinopiwa Goronga; Qin Jiang; Xiaoli Cui; Judith Hyle; Jill M Lahti; Stephan W Morris; Thomas R Webb
Journal: J Med Chem Date: 2009-11-26 Impact factor: 7.446

2. Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA.

Authors: Roberto H Herai; Priscilla D Negraes; Alysson R Muotri
Journal: Hum Mol Genet Date: 2017-07-01 Impact factor: 6.150

3. Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling.

Authors: Yaping Lin-Moshier; Peter J Sebastian; Leeann Higgins; Natalie D Sampson; Jane E Hewitt; Jonathan S Marchant
Journal: J Biol Chem Date: 2012-11-12 Impact factor: 5.157

4. Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.

Authors: Yesim Gökmen-Polar; Yaseswini Neelamraju; Chirayu P Goswami; Xiaoping Gu; Gouthami Nallamothu; Sarath Chandra Janga; Sunil Badve
Journal: Mod Pathol Date: 2014-11-28 Impact factor: 7.842

10. Optimization of a Bioluminescence Resonance Energy Transfer-Based Assay for Screening of Trypanosoma cruzi Protein/Protein Interaction Inhibitors.

Authors: Jesica G Mild; Lucia R Fernandez; Odile Gayet; Juan Iovanna; Nelson Dusetti; Martin M Edreira
Journal: Mol Biotechnol Date: 2018-05 Impact factor: 2.695

Targeting the spliceosome.

1. Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.

2. Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA.

3. Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling.

4. Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.

Review 5. Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective.

Review 6. The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression.

7. Enantioselective Synthesis of Spliceostatin G and Evaluation of Bioactivity of Spliceostatin G and Its Methyl Ester.

8. Antitumor compounds based on a natural product consensus pharmacophore.

9. Design, synthesis and in vitro splicing inhibition of desmethyl and carba-derivatives of herboxidiene.

10. Optimization of a Bioluminescence Resonance Energy Transfer-Based Assay for Screening of Trypanosoma cruzi Protein/Protein Interaction Inhibitors.