Literature DB >> 176998

Expression of the human adenylate kinase isozymes, phosphopyruvate hydratase, 6-phosphogluconate dehydrogenase, and phosphoglucomutase-1 in man-rodent somatic cell hybrids.

G A Bruns, P S Gerald.   

Abstract

The expression of the adenylate kinase isozymes and of phosphopyruvate hydratase was studied in man-mouse and man-hamster hybrid clones. Concordant segregation of the loci coding for AK-2 and PPH was observed in 54 of 55 primary hybrid clones, and these loci were demonstrated to be synthetic with the loci specifying PGM-1 and PGD. The pattern of expression of the four enzymes in discordant clone suggests the gene order 1pter-(PGD, PPH)-AK-2-PGM-1-centromere. In addition, AK-1 was found to be expressed independently of AK-2.

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Year:  1976        PMID： 176998     DOI： 10.1007/bf00484869

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  31 in total

1.  A -glucuronidase deficiency mucopolysaccharidosis: studies in cultured fibroblasts.

Authors:  C W Hall; M Cantz; E F Neufeld
Journal:  Arch Biochem Biophys       Date:  1973-03       Impact factor: 4.013

2.  Partial purification and properties of the two common inherited forms of human erythrocyte adenylate kinase.

Authors:  C Brownson; N Spencer
Journal:  Biochem J       Date:  1972-12       Impact factor: 3.857

3.  Polymorphism and linkage for mannosephosphate isomerase in Mus musculus.

Authors:  E A Nichols; V M Chapman; F H Ruddle
Journal:  Biochem Genet       Date:  1973-01       Impact factor: 1.890

4.  The use of drug-resistant markers to study the hybridization of mouse fibroblasts.

Authors:  J W Littlefield
Journal:  Exp Cell Res       Date:  1966-01       Impact factor: 3.905

5.  The genetic linkage relations of adenylate kinase: further data on the ABO-AK linkage group.

Authors:  L R Weitkamp; C F Sing; D C Shreffler; S A Guttormsen
Journal:  Am J Hum Genet       Date:  1969-11       Impact factor: 11.025

6.  Evidence for linkage between human loci for 6-phosphogluconate dehydrogenase and phosphoglucomutase in man-Chinese hamster somatic cell hybrids.

Authors:  A Westerveld; P Meera Khan
Journal:  Nature       Date:  1972-03-03       Impact factor: 49.962

7.  Regional localization of loci for human PGM and 6PGD on human chromosome one by use of hybrids of Chinese hamster-human somatic cells.

Authors:  G R Douglas; P J McAlpine; J L Hamerton
Journal:  Proc Natl Acad Sci U S A       Date:  1973-10       Impact factor: 11.205

8.  Somatic cell genetic assignment of peptidase C and the Rh linkage group to chromosome A-1 in man.

Authors:  F Ruddle; F Ricciuti; F A McMorris; G Darlington; T Chen
Journal:  Science       Date:  1972-06-30       Impact factor: 47.728

9.  Human acid phosphatase in somatic cell hybrids.

Authors:  G A Bruns; P S Gerald
Journal:  Science       Date:  1974-04-26       Impact factor: 47.728

10.  Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes.

Authors:  M C Weiss; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1967-09       Impact factor: 11.205
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  3 in total

1.  Expression of alpha-D-mannosidase in man-hamster somatic cell hybrids.

Authors:  P H Ingram; G A Bruns; V M Regina; R E Eisenman; P S Gerald
Journal:  Biochem Genet       Date:  1977-06       Impact factor: 1.890

2.  Comparative mapping using somatic cell hybrids.

Authors:  J D Minna; P A Lalley; U Francke
Journal:  In Vitro       Date:  1976-11

3.  Adenylate kinase 2, a mitochondrial enzyme.

Authors:  G A Bruns; V M Regina
Journal:  Biochem Genet       Date:  1977-06       Impact factor: 1.890
  3 in total

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