Literature DB >> 17698619

Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans.

Isabella Rauch1, Linda Lundström, Markus Hell, Wolfgang Sperl, Barbara Kofler.   

Abstract

The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

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Year:  2007        PMID: 17698619      PMCID: PMC2151459          DOI: 10.1128/AAC.00166-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  17 in total

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Authors:  Barbara Kofler; Alexander Berger; Radmila Santic; Kerstin Moritz; Dietmer Almer; Camilla Tuechler; Roland Lang; Michael Emberger; Alfred Klausegger; Wolfgang Sperl; Johann W Bauer
Journal:  J Invest Dermatol       Date:  2004-04       Impact factor: 8.551

Review 2.  The nervous system and innate immunity: the neuropeptide connection.

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Review 4.  Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence.

Authors:  Carol A Kumamoto; Marcelo D Vinces
Journal:  Cell Microbiol       Date:  2005-11       Impact factor: 3.715

5.  Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases.

Authors:  Miriam Wittmann; Rahul Purwar; Christina Hartmann; Ralf Gutzmer; Thomas Werfel
Journal:  J Invest Dermatol       Date:  2005-06       Impact factor: 8.551

6.  Galanin - a novel biologically active peptide from porcine intestine.

Authors:  K Tatemoto; A Rökaeus; H Jörnvall; T J McDonald; V Mutt
Journal:  FEBS Lett       Date:  1983-11-28       Impact factor: 4.124

Review 7.  Galanin and galanin receptors in epilepsy.

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9.  Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes.

Authors:  E Schauer; F Trautinger; A Köck; A Schwarz; R Bhardwaj; M Simon; J C Ansel; T Schwarz; T A Luger
Journal:  J Clin Invest       Date:  1994-05       Impact factor: 14.808

10.  Interleukin-1, tumor necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells.

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  6 in total

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Review 2.  Mammalian Neuropeptides as Modulators of Microbial Infections: Their Dual Role in Defense versus Virulence and Pathogenesis.

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4.  Galanin receptors and ligands.

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5.  Gut microbiota composition in colorectal cancer patients is genetically regulated.

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  6 in total

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