Literature DB >> 17693958

Synthesis of functionalised nucleosides for incorporation into nucleic acid-based serine protease mimics.

Mieke A Catry1, Annemieke Madder.   

Abstract

The synthesis of nucleosides modified with an extra imidazole, carboxyl and hydroxyl group is described. These nucleosides can be incorporated into an oligonucleotide duplex, thus generating a novel type of serine protease mimic.

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Year:  2007        PMID： 17693958      PMCID： PMC6149322          DOI： 10.3390/12010114

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  32 in total

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3.  Application of Combinatorial Procedures in the Search for Serine-Protease-Like Activity with Focus on the Acyl Transfer Step.

Authors: 
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4.  Synthesis and cleavage experiments of oligonucleotide conjugates with a diimidazole-derived catalytic center.

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Journal:  Bioconjug Chem       Date:  2002 Mar-Apr       Impact factor: 4.774

5.  Slow reversible inhibitions of rabbit muscle aldolase with substrate analogues: synthesis, enzymatic kinetics and UV difference spectroscopy studies.

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6.  A reinvestigation of a synthetic peptide (TrPepz) designed to mimic trypsin.

Authors:  J A Wells; W J Fairbrother; J Otlewski; M Laskowski; J Burnier
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

7.  Oligonucleotides with 2'-O-carboxymethyl group: synthesis and 2'-conjugation via amide bond formation on solid phase.

Authors:  Anna Kachalova; Eugeny Zubin; Dmitry Stetsenko; Michael Gait; Tatiana Oretskaya
Journal:  Org Biomol Chem       Date:  2004-09-03       Impact factor: 3.876

8.  Synthesis and properties of oligo-2'-deoxyribonucleotides containing internucleotidic phosphoramidate linkages modified with pendant groups ending with either two amino or two hydroxyl functions.

Authors:  Ulysse Asseline; Marcel Chassignol; Jolanta Draus; Maurice Durand; Jean Claude Maurizot
Journal:  Bioorg Med Chem       Date:  2003-08-05       Impact factor: 3.641

9.  Studies on chymotrypsin-like catalysis by synthetic peptides.

Authors:  M J Corey; E Hallakova; K Pugh; J M Stewart
Journal:  Appl Biochem Biotechnol       Date:  1994 May-Jun       Impact factor: 2.926

10.  Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines.

Authors:  Leonard Lermer; Yoann Roupioz; Richard Ting; David M Perrin
Journal:  J Am Chem Soc       Date:  2002-08-28       Impact factor: 15.419
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  5 in total

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2.  Versatile synthesis of amino acid functionalized nucleosides via a domino carboxamidation reaction.

Authors:  Vicky Gheerardijn; Jos Van den Begin; Annemieke Madder
Journal:  Beilstein J Org Chem       Date:  2014-11-04       Impact factor: 2.883

3.  Effective Synthesis of Nucleosides Utilizing O-Acetyl-Glycosyl Chlorides as Glycosyl Donors in the Absence of Catalyst: Mechanism Revision and Application to Silyl-Hilbert-Johnson Reaction.

Authors:  Chengyuan Liang; Weihui Ju; Shunjun Ding; Han Sun; Gennian Mao
Journal:  Molecules       Date:  2017-01-05       Impact factor: 4.411

Review 4.  Convertible and Constrained Nucleotides: The 2'-Deoxyribose 5'-C-Functionalization Approach, a French Touch.

Authors:  Crystalle Chardet; Corinne Payrastre; Béatrice Gerland; Jean-Marc Escudier
Journal:  Molecules       Date:  2021-09-30       Impact factor: 4.411

5.  DNA Three Way Junction Core Decorated with Amino Acids-Like Residues-Synthesis and Characterization.

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  5 in total

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