Literature DB >> 17690556

Incidence and outcome of traumatic brain injury in an urban area in Western Europe over 10 years.

M Maegele1, D Engel, B Bouillon, R Lefering, H Fach, M Raum, B Buchheister, U Schaefer, N Klug, E Neugebauer.   

Abstract

INTRODUCTION: Valid epidemiological data on incidence and outcome of traumatic brain injury (TBI) show great variability. A study on incidence, severity and outcome of TBI was conducted in an urban area of one million inhabitants.
MATERIALS AND METHODS: 130,000 prehospital emergencies were screened for TBI. INCLUSION CRITERIA: Glasgow Coma Scale (GCS) score <or=8 and/or Abbreviated Injury Scale for head injuries (AIS(head)) score >or=2 with confirmed TBI via appropriate diagnostics.
RESULTS: Annual incidence was 7.3/100,000. Overall mortality rate was 45.8%: 182 (28%) were prehospital deaths, 116 (17.8%) patients died in hospital. Two hundred and fourteen of 352 (60.8%) surviving patients were sufficiently rehabilitated at discharge [Glasgow Outcome Scale (GOS) score = 1], but 138 patients (39.2%) survived with persisting deficits. GOS was associated with initial GCS and AIS(head).
CONCLUSION: The incidence of TBI was lower compared to the literature. The overall mortality was high, especially prehospital and early in-hospital mortality rates. (c) 2007 S. Karger AG, Basel.

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Year:  2007        PMID: 17690556     DOI: 10.1159/000107097

Source DB:  PubMed          Journal:  Eur Surg Res        ISSN: 0014-312X            Impact factor:   1.745


  19 in total

1.  Severe traumatic injury: regional variation in incidence and outcome.

Authors:  Joseph P Minei; Robert H Schmicker; Jeffrey D Kerby; Ian G Stiell; Martin A Schreiber; Eileen Bulger; Samuel Tisherman; David B Hoyt; Graham Nichol
Journal:  Ann Surg       Date:  2010-07       Impact factor: 12.969

2.  [Urgency of neurosurgical interventions for severe traumatic brain injury].

Authors:  C A Kühne; C Mand; R Lefering; S Lendemans; S Ruchholtz
Journal:  Unfallchirurg       Date:  2013-01       Impact factor: 1.000

3.  Experimental traumatic brain injury.

Authors:  Christiane Albert-Weissenberger; Anna-Leena Sirén
Journal:  Exp Transl Stroke Med       Date:  2010-08-13

4.  [Treatment of traumatic brain injury in Germany].

Authors:  E Rickels; K von Wild; P Wenzlaff
Journal:  Unfallchirurg       Date:  2011-05       Impact factor: 1.000

5.  The Incidence and Management of Moderate to Severe Head Injury.

Authors:  Marc Maegele; Rolf Lefering; Oliver Sakowitz; Marcel A Kopp; Jan M Schwab; Wolf-Ingo Steudel; Andreas Unterberg; Reinhard Hoffmann; Eberhard Uhl; Ingo Marzi
Journal:  Dtsch Arztebl Int       Date:  2019-03-08       Impact factor: 5.594

6.  Upregulation of CRM1 relates to neuronal apoptosis after traumatic brain injury in adult rats.

Authors:  Aihong Li; Feihui Zou; Hongran Fu; Gang Cui; Yaohua Yan; Qiyun Wu; Xingxing Gu
Journal:  J Mol Neurosci       Date:  2013-03-15       Impact factor: 3.444

7.  Epidemiologic study in hospitalized patients with head injuries.

Authors:  Y Aras; P A Sabanci; T C Unal; A Aydoseli; N Izgi
Journal:  Eur J Trauma Emerg Surg       Date:  2016-04-09       Impact factor: 3.693

8.  Epidemiology of in-hospital trauma deaths.

Authors:  R Lefering; T Paffrath; O Bouamra; T J Coats; M Woodford; T Jenks; A Wafaisade; U Nienaber; F Lecky
Journal:  Eur J Trauma Emerg Surg       Date:  2011-12-13       Impact factor: 3.693

Review 9.  Mechanosensation in traumatic brain injury.

Authors:  Carolyn E Keating; D Kacy Cullen
Journal:  Neurobiol Dis       Date:  2020-11-28       Impact factor: 5.996

10.  An experimental protocol for mimicking pathomechanisms of traumatic brain injury in mice.

Authors:  Christiane Albert-Weißenberger; Csanád Várrallyay; Furat Raslan; Christoph Kleinschnitz; Anna-Leena Sirén
Journal:  Exp Transl Stroke Med       Date:  2012-02-02
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